Daniel Geschwind
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Explore the profile of Daniel Geschwind including associated specialties, affiliations and a list of published articles.
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58
Citations
4197
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Recent Articles
1.
Sun Y, Wang X, Zhang D, Zhang Z, Bhattarai J, Wang Y, et al.
Nature
. 2025 Jan;
PMID: 39821165
Glioblastoma (GBM) infiltrates the brain and can be synaptically innervated by neurons, which drives tumour progression. Synaptic inputs onto GBM cells identified so far are largely short range and glutamatergic....
2.
Emani P, Liu J, Clarke D, Jensen M, Warrell J, Gupta C, et al.
Science
. 2024 May;
384(6698):eadi5199.
PMID: 38781369
Single-cell genomics is a powerful tool for studying heterogeneous tissues such as the brain. Yet little is understood about how genetic variants influence cell-level gene expression. Addressing this, we uniformly...
3.
Pressman P, Carter D, Ramos E, Molden J, Smith K, Dino F, et al.
Neurocase
. 2024 May;
30(1):39-47.
PMID: 38757415
We present a longitudinal description of a man with the I383V variant of frontotemporal dementia (FTD). His progressive changes in behavior and language resulted in a diagnosis of the right...
4.
Stackpole M, Zeng W, Li S, Liu C, Zhou Y, He S, et al.
Nat Commun
. 2024 May;
15(1):3693.
PMID: 38693151
No abstract available.
5.
Vandebergh M, Ramos E, Corriveau-Lecavalier N, Ramanan V, Kornak J, Mester C, et al.
medRxiv
. 2024 Apr;
PMID: 38633784
Background And Objectives: has been proposed as a modifier of disease risk in FTLD-TDP, particularly in mutation carriers. Furthermore, has been investigated as a disease modifier in the context of...
6.
Curto Y, Carceller H, Klimczak P, Perez-Rando M, Wang Q, Grewe K, et al.
Mol Psychiatry
. 2024 Apr;
29(10):2979-2996.
PMID: 38622200
Severe psychiatric illnesses, for instance schizophrenia, and affective diseases or autism spectrum disorders, have been associated with cognitive impairment and perturbed excitatory-inhibitory balance in the brain. Effects in juvenile mice...
7.
Saloner R, Staffaroni A, Dammer E, Johnson E, Paolillo E, Wise A, et al.
Res Sq
. 2024 Apr;
PMID: 38585969
The pathophysiological mechanisms driving disease progression of frontotemporal lobar degeneration (FTLD) and corresponding biomarkers are not fully understood. We leveraged aptamer-based proteomics (> 4,000 proteins) to identify dysregulated communities of...
8.
Gaynor-Gillett S, Cheng L, Shi M, Liu J, Wang G, Spector M, et al.
bioRxiv
. 2024 Apr;
PMID: 38562832
Genome-wide association studies (GWAS) and expression analyses implicate noncoding regulatory regions as harboring risk factors for psychiatric disease, but functional characterization of these regions remains limited. We performed capture STARR-sequencing...
9.
Emani P, Liu J, Clarke D, Jensen M, Warrell J, Gupta C, et al.
bioRxiv
. 2024 Apr;
PMID: 38562822
Single-cell genomics is a powerful tool for studying heterogeneous tissues such as the brain. Yet, little is understood about how genetic variants influence cell-level gene expression. Addressing this, we uniformly...
10.
Staffaroni A, Clark A, Taylor J, Heuer H, Sanderson-Cimino M, Wise A, et al.
JAMA Netw Open
. 2024 Apr;
7(4):e244266.
PMID: 38558141
Importance: Frontotemporal lobar degeneration (FTLD) is relatively rare, behavioral and motor symptoms increase travel burden, and standard neuropsychological tests are not sensitive to early-stage disease. Remote smartphone-based cognitive assessments could...