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Daniel F Aubert

Explore the profile of Daniel F Aubert including associated specialties, affiliations and a list of published articles. Areas
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Citations 395
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Recent Articles
1.
Rosales-Reyes R, Garza-Villafuerte P, Vences-Vences D, Aubert D, Aca-Teutle R, Ortiz-Navarrete V, et al.
Emerg Microbes Infect . 2020 Sep; 9(1):2000-2012. PMID: 32873215
Burkholderia cenocepacia is an emerging opportunistic pathogen for people with cystic fibrosis and chronic granulomatous disease. Intracellular survival in macrophages within a membrane-bound vacuole (BcCV) that delays acidification and maturation...
2.
Aubert D, Xu H, Yang J, Shi X, Gao W, Li L, et al.
Cell Host Microbe . 2016 May; 19(5):664-74. PMID: 27133449
Burkholderia cenocepacia is an opportunistic pathogen of the cystic fibrosis lung that elicits a strong inflammatory response. B. cenocepacia employs a type VI secretion system (T6SS) to survive in macrophages...
3.
Aubert D, Hu S, Valvano M
Microbiology (Reading) . 2015 Sep; 161(11):2161-73. PMID: 26364149
The Gram-negative bacterial type VI secretion system (T6SS) delivers toxins to kill or inhibit the growth of susceptible bacteria, while other secretion systems target eukaryotic cells. Deletion of atsR, a...
4.
Aubert D, Hamad M, Valvano M
Methods Mol Biol . 2014 Aug; 1197:311-27. PMID: 25172289
Genetic manipulation of multidrug-resistant bacteria is often difficult and hinders progress in understanding their physiology and pathogenesis. This book chapter highlights advances in genetic manipulation of Burkholderia cenocepacia, which are...
5.
Khodai-Kalaki M, Aubert D, Valvano M
J Biol Chem . 2013 Sep; 288(42):30473-30484. PMID: 24014026
AtsR is a membrane-bound hybrid sensor kinase of Burkholderia cenocepacia that negatively regulates quorum sensing and virulence factors such as biofilm production, type 6-secretion, and protease secretion. Here we elucidate...
6.
Rosales-Reyes R, Aubert D, Tolman J, Amer A, Valvano M
PLoS One . 2012 Aug; 7(7):e41726. PMID: 22848580
Burkholderia cenocepacia is an opportunistic pathogen that survives intracellularly in macrophages and causes serious respiratory infections in patients with cystic fibrosis. We have previously shown that bacterial survival occurs in...
7.
Aubert D, OGrady E, Hamad M, Sokol P, Valvano M
Environ Microbiol . 2012 Jul; 15(2):372-85. PMID: 22830644
Burkholderia cenocepacia is commonly found in the environment and also as an important opportunistic pathogen infecting patients with cystic fibrosis. Successful infection by this bacterium requires coordinated expression of virulence...
8.
Rosales-Reyes R, Saldias M, Aubert D, El-Halfawy O, Valvano M
Microbiology (Reading) . 2012 Jul; 158(Pt 9):2315-2324. PMID: 22767545
Burkholderia cenocepacia is a member of the Burkholderia cepacia complex (Bcc), a group of Gram-negative opportunistic pathogens that cause severe lung infections in patients with cystic fibrosis and display extreme...
9.
Gavrilin M, Abdelaziz D, Mostafa M, Abdulrahman B, Grandhi J, Akhter A, et al.
J Immunol . 2012 Feb; 188(7):3469-77. PMID: 22368275
Burkholderia cenocepacia is an opportunistic pathogen that causes chronic infection and induces progressive respiratory inflammation in cystic fibrosis patients. Recognition of bacteria by mononuclear cells generally results in the activation...
10.
Rosales-Reyes R, Skeldon A, Aubert D, Valvano M
Cell Microbiol . 2011 Oct; 14(2):255-73. PMID: 22023353
Burkholderia cenocepacia is a Gram-negative opportunistic pathogen of patients with cystic fibrosis and chronic granulomatous disease. The bacterium survives intracellularly in macrophages within a membrane-bound vacuole (BcCV) that precludes the...