Daniel E Heinz
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Explore the profile of Daniel E Heinz including associated specialties, affiliations and a list of published articles.
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19
Citations
310
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Recent Articles
1.
Mackert S, Niemeyer C, Mecdad Y, Ebert T, Bajaj T, Durand S, et al.
bioRxiv
. 2024 Dec;
PMID: 39677641
Depression is a stress-associated disorder, and it represents a major global health issue. Its pathophysiology is complex and remains insufficiently understood, with current medications often showing limited efficacy and undesirable...
2.
Hofer S, Daskalaki I, Bergmann M, Friscic J, Zimmermann A, Mueller M, et al.
Nat Cell Biol
. 2024 Aug;
26(9):1571-1584.
PMID: 39117797
Caloric restriction and intermittent fasting prolong the lifespan and healthspan of model organisms and improve human health. The natural polyamine spermidine has been similarly linked to autophagy enhancement, geroprotection and...
3.
Stepan J, Heinz D, Dethloff F, Wiechmann S, Martinelli S, Hafner K, et al.
Sci Signal
. 2024 Apr;
17(834):eadj6603.
PMID: 38687825
The localization, number, and function of postsynaptic AMPA-type glutamate receptors (AMPARs) are crucial for synaptic plasticity, a cellular correlate for learning and memory. The Hippo pathway member WWC1 is an...
4.
Hartmann J, Bajaj T, Otten J, Klengel C, Ebert T, Gellner A, et al.
Nat Commun
. 2024 Mar;
15(1):2635.
PMID: 38528004
High levels of proinflammatory cytokines induce neurotoxicity and catalyze inflammation-driven neurodegeneration, but the specific release mechanisms from microglia remain elusive. Here we show that secretory autophagy (SA), a non-lytic modality...
5.
Hartmann J, Bajaj T, Otten J, Klengel C, Gellner A, Junglas E, et al.
bioRxiv
. 2023 Apr;
PMID: 37066393
High levels of proinflammatory cytokines induce neurotoxicity and catalyze inflammation-driven neurodegeneration, but the specific release mechanisms from microglia remain elusive. We demonstrate that secretory autophagy (SA), a non-lytic modality of...
6.
Balsevich G, Petrie G, Heinz D, Singh A, Aukema R, Hunker A, et al.
Elife
. 2023 Apr;
12.
PMID: 37039453
Fatty acid amide hydrolase (FAAH) degrades the endocannabinoid anandamide. A polymorphism in (FAAH C385A) reduces FAAH expression, increases anandamide levels, and increases the risk of obesity. Nevertheless, some studies have...
7.
Stepan J, Heinz D, Dethloff F, Bajaj T, Zellner A, Hafner K, et al.
Cell Rep
. 2022 Dec;
41(10):111766.
PMID: 36476872
Learning and memory rely on changes in postsynaptic glutamergic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type receptor (AMPAR) number, spatial organization, and function. The Hippo pathway component WW and C2 domain-containing protein 1 (WWC1)...
8.
Ruat J, Genewsky A, Heinz D, Kaltwasser S, Canteras N, Czisch M, et al.
iScience
. 2022 Jul;
25(7):104657.
PMID: 35845167
Although mice mostly communicate in the ultrasonic range, they also emit audible calls. We demonstrate that mice selectively bred for high anxiety-related behavior (HAB) have a high disposition for emitting...
9.
Ebert T, Heinz D, Almeida-Correa S, Cruz R, Dethloff F, Stark T, et al.
Front Aging Neurosci
. 2021 Dec;
13:731603.
PMID: 34867270
Dementia is a devastating age-related disorder. Its therapy would largely benefit from the identification of susceptible subjects at early, prodromal stages of the disease. To search for such prognostic markers...
10.
Ruat J, Hartmann A, Heinz D, Nemcova P, Stoffel R, Deussing J, et al.
Genes Brain Behav
. 2021 Oct;
20(8):e12775.
PMID: 34672092
The endocannabinoid system is an important regulator of the hormonal and behavioral stress responses, which critically involve corticotropin-releasing factor (CRF) and its receptors. While it has been shown that CRF...