Daniel D Carson
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Explore the profile of Daniel D Carson including associated specialties, affiliations and a list of published articles.
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69
Citations
1625
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Recent Articles
1.
McCowan C, Salmon D, Hu J, Pudakalakatti S, Whiting N, Davis J, et al.
Diagnostics (Basel)
. 2022 Mar;
12(3).
PMID: 35328163
Medical imaging devices often use automated processing that creates and displays a self-normalized image. When improperly executed, normalization can misrepresent information or result in an inaccurate analysis. In the case...
2.
Brasil da Costa F, Lewis M, Truong A, Carson D, Farach-Carson M
PLoS One
. 2020 May;
15(5):e0230354.
PMID: 32413029
Bone marrow stroma influences metastatic prostate cancer (PCa) progression, latency, and recurrence. At sites of PCa bone metastasis, cancer-associated fibroblasts and tumor-associated macrophages interact to establish a perlecan-rich desmoplastic stroma....
3.
Hubka K, Carson D, Harrington D, Farach-Carson M
Acta Biomater
. 2019 Jul;
97:385-398.
PMID: 31351252
Growth factor gradients orchestrate many biological processes including organogenesis, wound healing, cancer invasion, and metastasis. Heparin-binding growth factor (HBGF) gradients are established in living systems by proteoglycans including the extracellular...
4.
Carson D, Dharmaraj N, Wang P
Expert Rev Endocrinol Metab
. 2018 Oct;
3(4):463-471.
PMID: 30290438
MUC1 is a multifunctional cell surface glycoprotein that modulates cell adhesion, protects mucosa from infection and enzymatic attack, lubricates cell surfaces, participates in multiple signal-transduction pathways and is overexpressed by...
5.
Morgado M, Carson D
J Cell Biochem
. 2016 Jun;
118(1):163-171.
PMID: 27292441
CA125 is serum tumor marker consisting of an epitope carried by a portion of the extremely large (>3 MDa), heavily glycosylated cell surface transmembrane mucin, MUC16. In malignancies, membrane bound...
6.
Engel B, Bowser J, Broaddus R, Carson D
Oncotarget
. 2016 Apr;
7(22):32796-809.
PMID: 27092881
The current standard of care for endometrial cancer patients involves hysterectomy with adjuvant radiation and chemotherapy, with no effective treatment for advanced and metastatic disease. MUC1 is a large, heavily...
7.
Morgado M, Sutton M, Simmons M, Warren C, Lu Z, Constantinou P, et al.
Oncotarget
. 2016 Feb;
7(12):14871-84.
PMID: 26918940
Transmembrane mucins (TMs) are restricted to the apical surface of normal epithelia. In cancer, TMs not only are over-expressed, but also lose polarized distribution. MUC16/CA125 is a high molecular weight...
8.
Constantinou P, Morgado M, Carson D
Adv Anat Embryol Cell Biol
. 2015 Oct;
216:51-68.
PMID: 26450494
Transmembrane mucins (TMs) are extremely large, complex glycoproteins that line the apical surfaces of simple epithelia including those of the female reproductive tract. TMs provide a physical barrier consistent with...
9.
Engel B, Constantinou P, Sablatura L, Doty N, Carson D, Farach-Carson M, et al.
Adv Healthc Mater
. 2015 Jun;
4(11):1664-74.
PMID: 26059746
Validation of a high-throughput compatible 3D hyaluronic acid hydrogel coculture of cancer cells with stromal cells. The multilayered hyaluronic acid hydrogels improve drug screening predictability as evaluated with a panel...
10.
Chapela P, Broaddus R, Hawkins S, Lessey B, Carson D
J Cell Biochem
. 2015 Apr;
116(11):2649-57.
PMID: 25923310
MUC4, a transmembrane glycoprotein, interferes with cell adhesion, and promotes EGFR signaling in cancer. Studies in rat models have demonstrated steroid hormonal regulation of endometrial MUC4 expression. In this study,...