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Daniel Constantin

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Articles 14
Citations 155
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Recent Articles
1.
Chancellor A, Constantin D, Berloffa G, Yang Q, Nosi V, Loureiro J, et al.
Immunity . 2024 Dec; 58(2):431-447.e10. PMID: 39701104
The major histocompatibility complex (MHC) class I-related molecule MHC-class-I-related protein 1 (MR1) presents metabolites to distinct MR1-restricted T cell subsets, including mucosal-associated invariant T (MAIT) and MR1T cells. However, self-reactive...
2.
Constantin D, Nosi V, Kehrer N, Vacchini A, Chancellor A, Contassot E, et al.
Cancer Immunol Res . 2024 Jul; 12(10):1452-1467. PMID: 39028853
The MHC class I-related molecule MR1 is ubiquitously expressed, is highly conserved among mammals, and presents bacterial and endogenous antigens in tumor cells. These features indicate that tumor-specific T cells...
3.
Chancellor A, Simmons R, Khanolkar R, Nosi V, Beshirova A, Berloffa G, et al.
J Exp Med . 2023 Jun; 220(9). PMID: 37382893
Mucosal-associated invariant T (MAIT) cells use canonical semi-invariant T cell receptors (TCR) to recognize microbial riboflavin precursors displayed by the antigen-presenting molecule MR1. The extent of MAIT TCR crossreactivity toward...
4.
Constantin D, Dubuis G, Conde-Rubio M, Widmann C
FEBS J . 2021 Sep; 289(3):808-831. PMID: 34528388
The human genome contains 11 APOBEC (apolipoprotein B mRNA editing catalytic polypeptide-like) cytidine deaminases classified into four families. These proteins function mainly in innate antiviral immunity and can also restrict...
5.
Grigore L, Gorgoteanu D, Molder C, Alexa O, Oncioiu I, Stefan A, et al.
Sensors (Basel) . 2021 Mar; 21(5). PMID: 33669001
To protect the personnel of the intervention units operating in high-risk areas, it is necessary to introduce (autonomous/semi-autonomous) robotic intervention systems. Previous studies have shown that robotic intervention systems should...
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Constantin D, Widmann C
Cell Death Dis . 2020 Dec; 11(11):1019. PMID: 33257682
It is of clinical importance to identify biomarkers predicting the efficacy of DNA damaging drugs (genotoxins) so that nonresponders are not unduly exposed to the deleterious effects of otherwise inefficient...
8.
Nicolae C, OConnor M, Constantin D, Moldovan G
Oncogene . 2018 Apr; 37(27):3647-3656. PMID: 29622796
DNA damage exposure is a major modifier of cell fate in both normal and cancer tissues. In response to DNA damage, myeloid leukemia cells activate a poorly understood terminal differentiation...
9.
Shahrour M, Nicolae C, Edvardson S, Ashhab M, Galvan A, Constantin D, et al.
Neurogenetics . 2017 Feb; 18(2):119. PMID: 28190220
No abstract available.
10.
Shahrour M, Nicolae C, Edvardson S, Ashhab M, Galvan A, Constantin D, et al.
Neurogenetics . 2016 Sep; 17(4):227-232. PMID: 27624574
DNA repair mechanisms such as nucleotide excision repair (NER) and translesion synthesis (TLS) are dependent on proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory protein. Recently, homozygosity for p.Ser228Ile...