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Daniel Catchpoole

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Articles 71
Citations 2159
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Recent Articles
11.
Mayoh C, Gifford A, Terry R, Lau L, Wong M, Rao P, et al.
Genome Med . 2023 Apr; 15(1):20. PMID: 37013636
Background: Molecular profiling of the tumour immune microenvironment (TIME) has enabled the rational choice of immunotherapies in some adult cancers. In contrast, the TIME of paediatric cancers is relatively unexplored....
12.
Hurkmans E, Klumpers M, Dello Russo C, De Witte W, Guchelaar H, Gelderblom H, et al.
Front Pharmacol . 2023 Jan; 13:980309. PMID: 36699085
Hearing loss (ototoxicity) is a major adverse effect of cisplatin and carboplatin chemotherapy. The aim of this study is to identify novel genetic variants that play a role in platinum-induced...
13.
Hurkmans E, Koenderink J, van den Heuvel J, Versleijen-Jonkers Y, Hillebrandt-Roeffen M, Groothuismink J, et al.
Front Pharmacol . 2022 Nov; 13:1042989. PMID: 36438828
Despite (neo) adjuvant chemotherapy with cisplatin, doxorubicin and methotrexate, some patients with primary osteosarcoma progress during first-line systemic treatment and have a poor prognosis. In this study, we investigated whether...
14.
Lau C, Qu Z, Draper D, Quan R, Braytee A, Bluff A, et al.
Sci Rep . 2022 Jul; 12(1):11337. PMID: 35790803
The significant advancement of inexpensive and portable virtual reality (VR) and augmented reality devices has re-energised the research in the immersive analytics field. The immersive environment is different from a...
15.
Saletta F, Vilain R, Gupta A, Nagabushan S, Yuksel A, Catchpoole D, et al.
JCO Precis Oncol . 2022 Feb; 1:1-12. PMID: 35172499
Purpose: Programmed death-ligand 1 (PD-L1) expression represents a potential predictive biomarker of immune checkpoint blockade response. However, literature about the prevalence of PD-L1 expression in the pediatric cancer setting is...
16.
Maus Esfahani N, Catchpoole D, Kennedy P
Life (Basel) . 2021 Dec; 11(12). PMID: 34947833
Copy number variants (CNVs) are the most common form of structural genetic variation, reflecting the gain or loss of DNA segments compared with a reference genome. Studies have identified CNV...
17.
Maus Esfahani N, Catchpoole D, Khan J, Kennedy P
BMC Bioinformatics . 2021 Dec; 22(1):588. PMID: 34895138
Background: Copy number variants (CNVs) are the gain or loss of DNA segments in the genome. Studies have shown that CNVs are linked to various disorders, including autism, intellectual disability,...
18.
Brohl A, Sindiri S, Wei J, Milewski D, Chou H, Song Y, et al.
Cell Rep . 2021 Nov; 37(8):110047. PMID: 34818552
We perform an immunogenomics analysis utilizing whole-transcriptome sequencing of 657 pediatric extracranial solid cancer samples representing 14 diagnoses, and additionally utilize transcriptomes of 131 pediatric cancer cell lines and 147...
19.
Sylvester D, Chen Y, Grima N, Saletta F, Padhye B, Bennetts B, et al.
Genes Chromosomes Cancer . 2021 Oct; 61(2):81-93. PMID: 34687117
Identification of cancer-predisposing germline variants in childhood cancer patients is important for therapeutic decisions, disease surveillance and risk assessment for patients, and potentially, also for family members. We investigated the...
20.
Kim J, Light N, Subasri V, Young E, Wegman-Ostrosky T, Barkauskas D, et al.
JCO Precis Oncol . 2021 Jun; 5. PMID: 34095712
Materials And Methods: Genome sequencing of the discovery cohort (n = 273) and exome sequencing of the secondary cohort (n = 121) were conducted on germline DNA. Analyses were performed...