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Daniel C Wicke

Explore the profile of Daniel C Wicke including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Pincha M, Sundarasetty B, Salguero G, Gutzmer R, Garritsen H, Macke L, et al.
Hum Gene Ther Methods . 2012 Mar; 23(1):38-55. PMID: 22428979
SmartDCs (Self-differentiated Myeloid-derived Antigen-presenting-cells Reactive against Tumors) consist of highly viable dendritic cells (DCs) induced to differentiate with lentiviral vectors (LVs) after an overnight ex vivo transduction. Tricistronic vectors co-expressing...
2.
Heckl D, Wicke D, Brugman M, Meyer J, Schambach A, Busche G, et al.
Blood . 2011 Feb; 117(14):3737-47. PMID: 21289307
Thpo/Mpl signaling plays an important role in the maintenance of hematopoietic stem cells (HSCs) in addition to its role in megakaryopoiesis. Patients with inactivating mutations in Mpl develop thrombocytopenia and...
3.
Wicke D, Meyer J, Buesche G, Heckl D, Kreipe H, Li Z, et al.
Mol Ther . 2009 Oct; 18(2):343-52. PMID: 19844195
Signaling of the thrombopoietin (THPO) receptor MPL is critical for the maintenance of hematopoietic stem cells (HSCs) and megakaryocytic differentiation. Inherited loss-of-function mutations of MPL cause severe thrombocytopenia and aplastic...