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Bala Sai Sundarasetty

Explore the profile of Bala Sai Sundarasetty including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 197
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Recent Articles
1.
Coppin E, Sundarasetty B, Rahmig S, Blume J, Verheyden N, Bahlmann F, et al.
Leukemia . 2021 May; 35(12):3561-3567. PMID: 33976371
Humanized mouse models have become increasingly valuable tools to study human hematopoiesis and infectious diseases. However, human T-cell differentiation remains inefficient. We generated mice expressing human interleukin-7 (IL-7), a critical...
2.
Volk V, Reppas A, Robert P, Spineli L, Sundarasetty B, Theobald S, et al.
Front Immunol . 2017 Dec; 8:1709. PMID: 29276513
Mice transplanted with human cord blood-derived hematopoietic stem cells (HSCs) became a powerful experimental tool for studying the heterogeneity of human immune reconstitution and immune responses . Yet, analyses of...
3.
Pinho M, Sundarasetty B, Bergami-Santos P, Steponavicius-Cruz K, Ferreira A, Stripecke R, et al.
Cytotherapy . 2016 Mar; 18(4):570-80. PMID: 26971685
Background Aims: Dendritic cell (DC)-tumor cell hybrids have been used clinically in cancer immunotherapy, but their advantage over the simple mixture of tumor cells and DCs is still a matter...
4.
Sundarasetty B, Kloess S, Oberschmidt O, Naundorf S, Kuehlcke K, Daenthanasanmak A, et al.
J Transl Med . 2015 Jul; 13:240. PMID: 26198406
Background: Reactivation of latent viruses such as human cytomegalovirus (HCMV) after allogeneic hematopoietic stem cell transplantation (HSCT) results in high morbidity and mortality. Effective immunization against HCMV shortly after allo-HSCT...
5.
Daenthanasanmak A, Salguero G, Sundarasetty B, Waskow C, Cosgun K, Guzman C, et al.
Mol Ther Methods Clin Dev . 2015 Jun; 1:14060. PMID: 26052526
Human cytomegalovirus (HCMV) harmfully impacts survival after peripheral blood hematopoietic stem cell transplantation (PB-HSCT). Delayed immune reconstitution after cord blood (CB)-HSCT leads to even higher HCMV-related morbidity and mortality. Towards...
6.
Salguero G, Daenthanasanmak A, Munz C, Raykova A, Guzman C, Riese P, et al.
J Immunol . 2014 Apr; 192(10):4636-47. PMID: 24740501
De novo regeneration of immunity is a major problem after allogeneic hematopoietic stem cell transplantation (HCT). HCT modeling in severely compromised immune-deficient animals transplanted with human stem cells is currently...
7.
Rickmann M, Macke L, Sundarasetty B, Stamer K, Figueiredo C, Blasczyk R, et al.
Ann Hematol . 2013 Apr; 92(8):1079-90. PMID: 23616009
Relapse occurs frequently after treatment of acute myeloid leukemia (AML) patients with the FMS-like tyrosine kinase 3-internal tandem duplication (ITD) mutation. The availability of immunologic biomarkers to predict patients at...
8.
Sundarasetty B, Singh V, Salguero G, Geffers R, Rickmann M, Macke L, et al.
Hum Gene Ther . 2013 Jan; 24(2):220-37. PMID: 23311414
Wilms' tumor 1 antigen (WT1) is overexpressed in acute myeloid leukemia (AML), a high-risk neoplasm warranting development of novel immunotherapeutic approaches. Unfortunately, clinical immunotherapeutic use of WT1 peptides against AML...
9.
Daenthanasanmak A, Salguero G, Borchers S, Figueiredo C, Jacobs R, Sundarasetty B, et al.
Vaccine . 2012 Jun; 30(34):5118-31. PMID: 22691433
Integrase-defective lentiviral vectors (ID-LVs) show several hallmarks of conventional lentiviral vectors such as absence of cytotoxic effects and long-term expression in non-replicating target cells. The integration rate of ID-LVs into...
10.
Pincha M, Sundarasetty B, Salguero G, Gutzmer R, Garritsen H, Macke L, et al.
Hum Gene Ther Methods . 2012 Mar; 23(1):38-55. PMID: 22428979
SmartDCs (Self-differentiated Myeloid-derived Antigen-presenting-cells Reactive against Tumors) consist of highly viable dendritic cells (DCs) induced to differentiate with lentiviral vectors (LVs) after an overnight ex vivo transduction. Tricistronic vectors co-expressing...