Daniel A Glazier
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Explore the profile of Daniel A Glazier including associated specialties, affiliations and a list of published articles.
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8
Citations
72
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Recent Articles
1.
Glazier D, Liao J, Roberts B, Li X, Yang K, Stevens C, et al.
Bioconjug Chem
. 2020 Apr;
31(5):1213-1233.
PMID: 32227878
RNA plays a myriad of roles in the body including the coding, decoding, regulation, and expression of genes. RNA oligonucleotides have garnered significant interest as therapeutics via antisense oligonucleotides or...
2.
Rhodium-Catalyzed (5 + 2) and (5 + 1) Cycloadditions Using 1,4-Enynes as Five-Carbon Building Blocks
Blaszczyk S, Glazier D, Tang W
Acc Chem Res
. 2019 Dec;
53(1):231-243.
PMID: 31820914
Cycloaddition reactions are a hallmark in organic synthesis because they provide an efficient way to construct highly substituted carbo- and heterocycles found in natural products and pharmaceutical agents. Most cycloadditions...
3.
Blaszczyk S, Xiao G, Wen P, Hao H, Wu J, Wang B, et al.
Angew Chem Int Ed Engl
. 2019 May;
58(28):9542-9546.
PMID: 31066162
The site-selective functionalization of carbohydrates is an active area of research. Reported here is the surprising observation that the sterically encumbered adamantyl group directed site-selective acylation at the C2 position...
4.
Zhao C, Glazier D, Yang D, Yin D, Guzei I, Aristov M, et al.
Angew Chem Int Ed Engl
. 2018 Nov;
58(3):887-891.
PMID: 30476368
We have developed the first intermolecular hetero-[5+2] cycloaddition reaction between oxidopyrylium ylides and cyclic imines with excellent control of regio- and stereoselectivity. Surprisingly, divergent stereochemistry was observed depending on the...
5.
Xiao G, Cintron-Rosado G, Glazier D, Xi B, Liu C, Liu P, et al.
J Am Chem Soc
. 2017 Mar;
139(12):4346-4349.
PMID: 28297601
Site-selective functionalization of hydroxyl groups in carbohydrates is one of the long-standing challenges in chemistry. Using a pair of chiral catalysts, we now can differentiate the most prevalent trans-1,2-diols in...
6.
Song W, Li X, Yang K, Zhao X, Glazier D, Xi B, et al.
J Org Chem
. 2016 Aug;
81(18):8662.
PMID: 27564916
No abstract available.
7.
Song W, Li X, Yang K, Zhao X, Glazier D, Xi B, et al.
J Org Chem
. 2016 Mar;
81(7):2930-42.
PMID: 26963834
Polycyclic aromatic compounds are important constituents of pharmaceuticals and other materials. We have developed a series of Rh-catalyzed tandem carbonylative benzannulations for the synthesis of tri-, tetra-, and pentacyclic heterocycles...
8.
Wang H, Yang K, Yin D, Liu C, Glazier D, Tang W
Org Lett
. 2015 Oct;
17(21):5272-5.
PMID: 26484422
The control of the stereochemistry at the anomeric position is still one of the major challenges of synthetic carbohydrate chemistry. We have developed a new strategy consisting of a chiral...