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Daniel A Beard

Explore the profile of Daniel A Beard including associated specialties, affiliations and a list of published articles. Areas
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Articles 149
Citations 2707
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Recent Articles
11.
Kim S, Randall E, Jezek F, Beard D, Chesler N
Front Physiol . 2023 Sep; 14:1231688. PMID: 37745253
The left (LV) and right (RV) ventricles are linked biologically, hemodynamically, and mechanically, a phenomenon known as ventricular interdependence. While LV function has long been known to impact RV function,...
12.
Fleischman J, Van den Bergh F, Collins N, Bowers M, Beard D, Burant C
Mol Metab . 2023 Aug; 76:101793. PMID: 37625738
Objective: Cardiorespiratory fitness (CRF) is tightly linked with health and longevity and is implicated in metabolic flexibility and substrate metabolism. The high capacity runner (HCR) and low capacity runner (LCR)...
13.
Mazumder N, Jezek F, Tapper E, Beard D
Clin Transl Gastroenterol . 2023 Apr; 14(9):e00590. PMID: 37092902
Introduction: As liver disease progresses, scarring results in worsening hemodynamics ultimately culminating in portal hypertension. This process has classically been quantified through the portosystemic pressure gradient (PSG), which is clinically...
14.
Warne C, Essajee S, Tucker S, Figueroa C, Beard D, Dick G, et al.
Basic Res Cardiol . 2023 Mar; 118(1):12. PMID: 36988670
The coronary circulation has an innate ability to maintain constant blood flow over a wide range of perfusion pressures. However, the mechanisms responsible for coronary autoregulation remain a fundamental and...
15.
Choi H, Bhat A, Howington M, Schaller M, Cox R, Huang S, et al.
Nat Commun . 2023 Feb; 14(1):562. PMID: 36732543
Flavin containing monooxygenases (FMOs) are promiscuous enzymes known for metabolizing a wide range of exogenous compounds. In C. elegans, fmo-2 expression increases lifespan and healthspan downstream of multiple longevity-promoting pathways...
16.
Halbrook C, Thurston G, Boyer S, Anaraki C, Jimenez J, McCarthy A, et al.
Nat Cancer . 2022 Nov; 3(11):1386-1403. PMID: 36411320
The pancreatic tumor microenvironment drives deregulated nutrient availability. Accordingly, pancreatic cancer cells require metabolic adaptations to survive and proliferate. Pancreatic cancer subtypes have been characterized by transcriptional and functional differences,...
17.
Beard D, Marzban B, Li O, Campbell K, Janssen P, Chesler N, et al.
Biophys J . 2022 Aug; 121(17):3213-3223. PMID: 35918899
For patients with heart failure, myocardial ATP level can be reduced to one-half of that observed in healthy controls. This marked reduction (from ≈8 mM in healthy controls to as...
18.
Beard D, Hummel S, Jezek F
Function (Oxf) . 2022 Mar; 3(1):zqab066. PMID: 35330926
No abstract available.
19.
Gharahi H, Figueroa C, Tune J, Beard D
J Physiol . 2022 Feb; 600(8):1913-1932. PMID: 35156733
Coronary blood flow is tightly regulated to ensure that myocardial oxygen delivery meets local metabolic demand via the concurrent action of myogenic, neural and metabolic mechanisms. Although several competing hypotheses...
20.
Jezek F, Randall E, Carlson B, Beard D
J Mol Cell Cardiol . 2021 Oct; 163:33-55. PMID: 34626617
Blood flows and pressures throughout the human cardiovascular system are regulated in response to various dynamic perturbations, such as changes to peripheral demands in exercise, rapid changes in posture, or...