Dana A Baum
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Explore the profile of Dana A Baum including associated specialties, affiliations and a list of published articles.
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15
Citations
122
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Recent Articles
1.
Chiura T, Pham M, Baum D, Mak P
J Inorg Biochem
. 2025 Feb;
266:112843.
PMID: 39923492
Guanine quadruplexes are non-canonical DNA structures with various functions including transcription and translation regulation and telomere protection. These structures are known to bind the heme prosthetic group, resulting in heme-bound...
2.
Parvez A, Baum D
ACS Biomater Sci Eng
. 2024 Nov;
10(12):7507-7515.
PMID: 39570116
Hydrogels have become common in wound treatment because they form very stable and biocompatible environments that promote healing. However, due to the highly porous hydrogel structure, any therapeutic added to...
3.
Samuelian J, Gremminger T, Song Z, Poudyal R, Li J, Zhou Y, et al.
Nat Chem Biol
. 2022 Sep;
18(11):1263-1269.
PMID: 36097297
The discovery of ribozymes has inspired exploration of RNA's potential to serve as primordial catalysts in a hypothesized RNA world. Modern oxidoreductase enzymes employ differential binding between reduced and oxidized...
4.
TeSelle E, Baum D
Aptamers (Oxf)
. 2021 Jun;
2:82-87.
PMID: 34079924
Functional nucleic acids, including aptamers and deoxyribozymes, have become important in a variety of applications, particularly sensors. Aptamers are useful for recognition because of their ability to bind to targets...
5.
Emahi I, Gruenke P, Baum D
J Mol Evol
. 2015 Oct;
81(5-6):186-93.
PMID: 26498628
In vitro selection or SELEX has allowed for the identification of functional nucleic acids (FNAs) that can potentially mimic and replace protein enzymes. These FNAs likely interact with cofactors, just...
6.
Behera A, Schlund K, Mason A, Alila K, Han M, Grout R, et al.
Biopolymers
. 2013 Mar;
99(6):382-91.
PMID: 23529690
Deoxyribozyme and aptamer selections are typically conducted in aqueous buffer solutions. Using nonaqueous cosolvents in selection experiments will help expand the activity of deoxyribozymes with non-oligonucleotide substrates and will allow...
7.
Zhang M, Xu S, Minteer S, Baum D
J Am Chem Soc
. 2011 Sep;
133(40):15890-3.
PMID: 21902236
We examined the ability of a previously identified peroxidase deoxyribozyme to be employed as a catalyst in biofuel cells, as a possible replacement for oxidoreductase proteins. We constructed a biocathode...
8.
Alila K, Baum D
Chem Commun (Camb)
. 2011 Jan;
47(11):3227-9.
PMID: 21258742
We have engineered an RNA-branching deoxyribozyme to respond positively to ATP, resulting in modulated control of ligation activity that may be applicable to sensor and nanotechnology applications.
9.
Silverman S, Baum D
Methods Enzymol
. 2010 Oct;
469:95-117.
PMID: 20946786
Since their first identification by in vitro selection in 1994, deoxyribozymes have been developed to catalyze a variety of chemical reactions. The first DNA-catalyzed reaction was cleavage of a ribonucleotide...
10.
Pradeepkumar P, Hobartner C, Baum D, Silverman S
Angew Chem Int Ed Engl
. 2008 Jan;
47(9):1753-7.
PMID: 18214866
No abstract available.