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Dana A Baum

Explore the profile of Dana A Baum including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 122
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Recent Articles
11.
Patel M, Baum D, Silverman S
Bioorg Chem . 2007 Nov; 36(2):46-56. PMID: 18022669
DNA with a 5'-adenylpyrophosphoryl cap (5'-adenylated DNA; AppDNA) is an activated form of DNA that is the biochemical intermediate of the reactions catalyzed by DNA ligase, RNA ligase, polynucleotide kinase,...
12.
Baum D, Silverman S
Angew Chem Int Ed Engl . 2007 Mar; 46(19):3502-4. PMID: 17394278
No abstract available.
13.
Alexander R, Baum D, Testa S
Biochemistry . 2005 May; 44(21):7796-804. PMID: 15909994
Group I intron-derived ribozymes can perform a variety of catalytic reactions, including the replacement of the 3' end of a mutant RNA transcript with a corrected version of the transcript...
14.
Baum D, Testa S
RNA . 2005 May; 11(6):897-905. PMID: 15872183
We have previously reported the development of a group I intron-derived ribozyme that can bind an exogenous RNA substrate and excise from that substrate an internal segment in vitro, which...
15.
Baum D, Sinha J, Testa S
Biochemistry . 2005 Jan; 44(3):1067-77. PMID: 15654763
Trans excision-splicing (TES) ribozymes, derived from a Pneumocystis carinii group I intron, can catalyze the excision of targeted sequences from within RNAs. In this report, the sequence requirements of the...
16.
Johnson A, Baum D, Tye J, Bell M, Testa S
Nucleic Acids Res . 2003 Mar; 31(7):1921-34. PMID: 12655009
We report the development, analysis and use of a new combinatorial approach to analyze the substrate sequence dependence of the suicide inhibition, cyclization, and reverse cyclization reactions catalyzed by a...