Dan Drecktrah
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Explore the profile of Dan Drecktrah including associated specialties, affiliations and a list of published articles.
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26
Citations
783
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Recent Articles
1.
Faith D, Kinnersley M, Brooks D, Drecktrah D, Hall L, Luo E, et al.
PLoS Pathog
. 2024 Apr;
20(4):e1012122.
PMID: 38558079
Lyme disease is a tick-borne infection caused by the spirochete Borrelia (Borreliella) burgdorferi. Borrelia species have highly fragmented genomes composed of a linear chromosome and a constellation of linear and...
2.
Faith D, Kinnersley M, Brooks D, Drecktrah D, Hall L, Luo E, et al.
bioRxiv
. 2024 Jan;
PMID: 38260690
Lyme disease is a tick-borne infection caused by the spirochete () . species have highly fragmented genomes composed of a linear chromosome and a constellation of linear and circular plasmids...
3.
Van Gundy T, Patel D, Bowler B, Rothfuss M, Hall A, Davies C, et al.
Mol Microbiol
. 2023 Apr;
119(6):711-727.
PMID: 37086029
PlzA is a c-di-GMP-binding protein crucial for adaptation of the Lyme disease spirochete Borrelia (Borreliella) burgdorferi during its enzootic life cycle. Unliganded apo-PlzA is important for vertebrate infection, while liganded...
4.
Drecktrah D, Hall L, Crouse B, Schwarz B, Richards C, Bohrnsen E, et al.
PLoS Pathog
. 2022 Mar;
18(3):e1010385.
PMID: 35255112
We have identified GpsA, a predicted glycerol-3-phosphate dehydrogenase, as a virulence factor in the Lyme disease spirochete Borrelia (Borreliella) burgdorferi: GpsA is essential for murine infection and crucial for persistence...
5.
Samuels D, Lybecker M, Yang X, Ouyang Z, Bourret T, Boyle W, et al.
Curr Issues Mol Biol
. 2020 Dec;
42:223-266.
PMID: 33300497
() , along with closely related species, is the etiologic agent of Lyme disease. The spirochete subsists in an enzootic cycle that encompasses acquisition from a vertebrate host to a...
6.
Pal U, Kitsou C, Drecktrah D, Yas O, Fikrig E
Curr Issues Mol Biol
. 2020 Dec;
42:113-144.
PMID: 33289683
sensu lato causes Lyme borreliosis in a variety of animals and humans. These atypical bacterial pathogens are maintained in a complex enzootic life cycle that primarily involves a vertebrate host...
7.
Drecktrah D, Hall L, Brinkworth A, Comstock J, Wassarman K, Samuels D
Mol Microbiol
. 2019 Nov;
113(2):399-417.
PMID: 31742773
6S RNA binds to RNA polymerase and regulates gene expression, contributing to bacterial adaptation to environmental stresses. In this study, we examined the role of 6S RNA in murine infectivity...
8.
Boyle W, Groshong A, Drecktrah D, Boylan J, Gherardini F, Blevins J, et al.
J Bacteriol
. 2018 Nov;
201(4).
PMID: 30478087
The pathogenic spirochete senses and responds to changes in the environment, including changes in nutrient availability, throughout its enzootic cycle in ticks and vertebrate hosts. This study examined the role...
9.
Drecktrah D, Hall L, Rescheneder P, Lybecker M, Samuels D
Front Cell Infect Microbiol
. 2018 Jul;
8:231.
PMID: 30027068
The Lyme disease spirochete () must tolerate nutrient stress to persist in the tick phase of its enzootic life cycle. We previously found that the stringent response mediated by Rel...
10.
Anacker M, Drecktrah D, LeCoultre R, Lybecker M, Samuels D
J Bacteriol
. 2018 Apr;
200(13).
PMID: 29632096
The rRNA genes of () are unusually organized; the spirochete has a single 16S rRNA gene that is more than 3 kb from a tandem pair of 23S-5S rRNA operons....