Dailin Gan
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Explore the profile of Dailin Gan including associated specialties, affiliations and a list of published articles.
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9
Citations
55
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Recent Articles
1.
Gan D, Li J
bioRxiv
. 2025 Mar;
PMID: 40027770
While foundation transformer-based models developed for gene expression data analysis can be costly to train and operate, a recent approach known as GenePT offers a low-cost and highly efficient alternative....
2.
Wang K, Li L, Kenny S, Gan D, Reitsma J, Zhou Y, et al.
Nat Commun
. 2025 Feb;
16(1):1998.
PMID: 40011427
Protein degradation orchestrated by SKP1·CUL1·F-box protein (SCF) ubiquitin ligases is a fundamental process essential for cellular and organismal function. The dynamic assembly of SCFs, facilitated by CAND1, ensures timely ubiquitination...
3.
Guo F, Gan D, Li J
Comput Struct Biotechnol J
. 2024 Nov;
23:3929-3937.
PMID: 39582889
The application of large-language models (LLMs) to single-cell gene-expression data has introduced a new type of data that includes a gene-embedding matrix, in addition to the experimentally obtained gene-expression matrix....
4.
Zhang Y, Hu J, Zhang X, Liang M, Wang X, Gan D, et al.
Cells
. 2024 May;
13(10).
PMID: 38786019
Myeloid-derived suppressor cells (MDSCs) play an essential role in suppressing the antitumor activity of T lymphocytes in solid tumors, thus representing an attractive therapeutic target to enhance the efficacy of...
5.
Gan D, Zhu Y, Lu X, Li J
Genome Biol
. 2024 May;
25(1):119.
PMID: 38741183
Numerous algorithms have been proposed to identify cell types in single-cell RNA sequencing data, yet a fundamental problem remains: determining associations between cells and phenotypes such as cancer. We develop...
6.
Murphy S, Rahmy S, Gan D, Liu G, Zhu Y, Manyak M, et al.
Cancer Res
. 2024 Apr;
84(10):1597-1612.
PMID: 38588411
Significance: Optimized cyclic ketogenic diet and 1,3-butanediol supplementation regimens enhance the efficacy of immune checkpoint blockade in prostate cancer through epigenetic and immune modulations, providing dietary interventions to sensitize tumors...
7.
Zhao Y, Liu Z, Liu G, Zhang Y, Liu S, Gan D, et al.
Cell Metab
. 2023 Oct;
35(10):1688-1703.e10.
PMID: 37793345
Metastasis causes breast cancer-related mortality. Tumor-infiltrating neutrophils (TINs) inflict immunosuppression and promote metastasis. Therapeutic debilitation of TINs may enhance immunotherapy, yet it remains a challenge to identify therapeutic targets highly...
8.
Murphy S, Rahmy S, Gan D, Zhu Y, Manyak M, Li J, et al.
bioRxiv
. 2023 Aug;
PMID: 37609341
Advanced prostate cancer (PCa) is overwhelmingly resistant to immune checkpoint blockade (ICB) therapy, representing a formidable clinical challenge. In this study, we developed a syngeneic murine PCa model with acquired...
9.
Gan D, Li J
Bioinformatics
. 2022 Dec;
39(1).
PMID: 36548380
Motivation: Integrative analysis of multiple single-cell RNA-sequencing datasets allows for more comprehensive characterizations of cell types, but systematic technical differences between datasets, known as 'batch effects', need to be removed...
10.
Gan D, Yin G, Zhang Y
Brief Bioinform
. 2022 Oct;
23(6).
PMID: 36184191
Biological networks are important for the analysis of human diseases, which summarize the regulatory interactions and other relationships between different molecules. Understanding and constructing networks for molecules, such as DNA,...