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Dai-Qiang Liu

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Articles 35
Citations 549
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Recent Articles
1.
Wu J, Wang W, Dai X, He S, Song F, Gao S, et al.
Br J Anaesth . 2024 Dec; 134(2):425-440. PMID: 39645516
Background: The supramammillary nucleus (SuM), located in the caudal hypothalamus, includes wake-promoting glutamatergic neurones. Their potential role in regulating states of consciousness during general anaesthesia remains unknown. Methods: We used...
2.
Liu L, Song F, Gao S, Wu J, Li D, Zhang L, et al.
Brain Res . 2024 Dec; 1850:149366. PMID: 39617285
Chronic pain represents an incapacitating medical condition that profoundly impacts the patients' quality of life. Managing chronic pain poses a significant challenge for healthcare professionals due to its multifaceted nature...
3.
Liu D, Mei W, Zhou Y, Xi H
Trends Pharmacol Sci . 2024 Jul; 45(10):862-867. PMID: 39019763
Transient receptor potential melastatin (TRPM) channels have emerged as potential therapeutic targets for cerebral ischemia-reperfusion (I/R) injury. We highlight recent findings on the involvement of TRPM channels in oxidative stress,...
4.
Chen N, Zhan R, Liu D, Zhang Y, Tian Y, Zhou Y
Biochem Pharmacol . 2024 Feb; 222:116053. PMID: 38354958
Cancer-induced bone pain (CIBP) stands out as one of the most challenging issues in clinical practice due to its intricate and not fully elucidated pathophysiological mechanisms. Existing evidence has pointed...
5.
Dai X, Liu L, Song F, Gao S, Wu J, Li D, et al.
Int J Biol Macromol . 2024 Jan; 261(Pt 1):129619. PMID: 38272407
Chronic pain constitutes an abnormal pain state that detrimentally affects the quality of life, daily activities, occupational performance, and stability of mood. Despite the prevalence of chronic pain, effective drugs...
6.
Gao S, Liu L, Li D, Liu D, Zhang L, Wu J, et al.
Curr Neuropharmacol . 2023 Aug; 22(2):204-216. PMID: 37581321
Pathological pain imposes a huge burden on the economy and the lives of patients. At present, drugs used for the treatment of pathological pain have only modest efficacy and are...
7.
Sun J, Wang X, Song F, Li D, Gao S, Zhang L, et al.
Br J Pharmacol . 2023 Jul; 180(24):3194-3214. PMID: 37485568
Background And Purpose: Osteoarthritis (OA) pain remains a major clinical problem. It is urgent to identify novel therapeutic approaches for OA pain states. Bromodomain and extra-terminal (BET) protein inhibitors have...
8.
Dai X, Liu L, Song F, Gao S, Wu J, Li D, et al.
Aging Dis . 2023 Jun; 15(1):186-200. PMID: 37307838
Chronic pain is a notable health concern because of its prevalence, persistence, and associated mental stress. Drugs targeting chronic pain with potent abirritation, and minimal side effects remain unidentified. Substantial...
9.
Li D, Gao S, Sun J, Zhang L, Wu J, Song F, et al.
Neural Regen Res . 2022 Oct; 18(5):996-1003. PMID: 36254980
Nitric oxide (NO)/cyclic guanosine 3',5'-monophosphate (cGMP) signaling has been shown to act as a mediator involved in pain transmission and processing. In this review, we summarize and discuss the mechanisms...
10.
Zhou Y, Liu D, Liu C, Xu A, Tian Y, Mei W, et al.
Front Mol Neurosci . 2022 Oct; 15:970040. PMID: 36245927
Despite rapid advances in the field of chronic pain, it remains extremely challenging in the clinic. Pain treatment strategies have not improved for decades as opioids remain the main prescribed...