Dahye Yoon
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Explore the profile of Dahye Yoon including associated specialties, affiliations and a list of published articles.
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65
Citations
409
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Recent Articles
1.
Jin Jung H, Kim H, Park H, Soo Park H, Ko J, Yoon D, et al.
Molecules
. 2025 Jan;
30(2).
PMID: 39860159
Fifteen compounds (-) constructed on a hybrid structure combining a β-phenyl-α,β-unsaturated carbonyl template and a 2-aminothiazol-4(5)-one scaffold were designed and synthesized as potential novel anti-tyrosinase substances. Two compounds ( and...
2.
Dong L, Choi B, Jeong H, Lee H, Liu Z, Yoon D, et al.
Plants (Basel)
. 2024 Oct;
13(19).
PMID: 39409690
To develop functional varieties of spp. leaves, 40 genetic resources were collected and extracted with 30% aqueous-fermented ethanol. We investigated the protective effects of extracts from 40 genetic resources of...
3.
Yoon D, Choi B, Kim H, Lee D
J Food Sci
. 2024 Oct;
89(11):7452-7463.
PMID: 39390639
Ginger, which is the rhizome of Zingiber officinale Roscoe, is widely distributed and consumed. The taste and aroma of ginger differ depending on its geographical origin. To distinguish the origin...
4.
Jin Jung H, Park H, Soo Park H, Kim H, Yoon D, Park Y, et al.
Molecules
. 2024 Sep;
29(17).
PMID: 39275009
Inspired by the potent tyrosinase inhibitory activity of phenolic compounds with a 2-phenylbenzo[]thiazole scaffold, we explored phenolic compounds - with 2-phenylbenzo[]oxazole, which is isosterically related to 2-phenylbenzo[]thiazole, as novel tyrosinase...
5.
Yoon D, Oh S, Na H, Choi B, Kim K, Lee Y, et al.
Sci Rep
. 2024 Jul;
14(1):17007.
PMID: 39043762
Population aging around the world is rapidly progressing; as a result, cognitive decline developing into dementia is becoming a social problem. There is no drug that can cure dementia, and...
6.
Jung Park Y, Jin Jung H, Kyung Kang M, Lee J, Yoon D, Soo Park H, et al.
Bioorg Med Chem
. 2024 Jul;
110:117832.
PMID: 39002182
Tyrosinase is a metalloenzyme that contains copper(II) ions. We designed and synthesized eight known low-molecular-weight 2-mercaptobenzoxazole (2-MBO) analogs as tyrosinase inhibitors. Our focus was on the mercapto functional group, which...
7.
Jin Jung H, Kim H, Soo Park H, Young Kim G, Jung Park Y, Lee J, et al.
Bioorg Chem
. 2024 Jul;
150:107586.
PMID: 38955001
Compounds with sulfhydryl substituents and azole compounds exhibit potent anti-tyrosinase potency. 2-Thiobenzothiazole (2-TBT), a hybrid structure of sulfhydryl and azole, exists in two tautomeric forms, with the thione form being...
8.
Yoon D, Jin Jung H, Lee J, Kim H, Soo Park H, Jung Park Y, et al.
Eur J Med Chem
. 2024 Jan;
266:116136.
PMID: 38244374
Recently, 10 2-mercaptobenzo[d]imidazole (2-MBI) compounds (1-10) were synthesized. Although all 2-MBI compounds are tyrosinase inhibitors that inhibit mushroom tyrosinase at extremely low concentrations (IC values: 20-740 nM) and effectively inhibit...
9.
Jung Park Y, Jin Jung H, Kim H, Soo Park H, Lee J, Yoon D, et al.
Bioorg Med Chem
. 2023 Dec;
98:117578.
PMID: 38154348
As the β-phenyl-α,β-unsaturated carbonyl (PUSC) structure was previously identified to play a key role in tyrosinase inhibition, 14 analogs with a PUSC structure built on a thiazol-4(5H)-one scaffold were synthesized...
10.
Ahn Y, Jang J, Kang Y, Oh H, Kyung Kang M, Yoon D, et al.
J Chemother
. 2023 Dec;
36(6):483-500.
PMID: 38054850
This study investigated the potential of a newly synthesized histone deacetylase (HDAC) inhibitor, MHY446, in inducing cell death in HCT116 colorectal cancer cells and compared its activity with that of...