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Dahong Long

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Articles 26
Citations 701
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Recent Articles
11.
Xu L, Long J, Shi C, Zhang N, Lv Y, Feng J, et al.
Int J Mol Med . 2018 Feb; 41(4):2037-2049. PMID: 29393372
Direct derivation of human induced pluripotent stem cells into neural precursor cells and differentiation of these into neurons holds great promise in the cell therapy of neurodegenerative diseases. However, the...
12.
Ou Z, Kong X, Sun X, He X, Zhang L, Gong Z, et al.
Brain Behav Immun . 2017 Dec; 69:351-363. PMID: 29253574
Alzheimer'sdisease(AD) is characterized by deposition of amyloid-β (Aβ)plaques, neurofibrillary tangles, andneuronal loss, accompaniedbyneuroinflammation. Neuroinflammatoryprocesses are thought to contribute toAD pathophysiology. Metformin has been reported to have anti-inflammatory efficacy. However, whether...
13.
Zhu X, Huang L, Gong J, Shi C, Wang Z, Ye B, et al.
Cell Death Discov . 2017 Sep; 3:17059. PMID: 28904818
Targeting endoplasmic reticulum (ER) stress is being investigated for its anticancer effect in various cancers, including cervical cancer. However, the molecular pathways whereby ER stress mediates cell death remain to...
14.
Zhang N, Lyu Y, Pan X, Xu L, Xuan A, He X, et al.
Int J Mol Med . 2017 Jul; 40(3):814-824. PMID: 28713933
Pluripotent stem cells (PSCs) are regarded as potential sources that provide specific neural cells for cell therapy in some nervous system diseases. However, the mechanisms underlying the neural differentiation of...
15.
Zhang X, He X, Li Q, Kong X, Ou Z, Zhang L, et al.
Stem Cell Reports . 2017 May; 8(5):1256-1269. PMID: 28494938
Although valproic acid (VPA), has been shown to induce neuronal differentiation of neural stem cells (NSCs), the underlying mechanisms remain poorly understood. Here we investigated if and how mammalian target...
16.
Shi C, Zhu J, Leng S, Long D, Luo X
J Bioenerg Biomembr . 2016 Jan; 48(3):189-96. PMID: 26782277
Mitochondrial dysfunction is a hallmark of amyloid β peptide (Aβ)-induced neuronal toxicity in Alzheimer's disease (AD). However, the precise mechanism(s) of Aβ-induced mitochondrial dysfunction has not been fully understood. There...
17.
Chen Y, Pan C, Xuan A, Xu L, Bao G, Liu F, et al.
Med Sci Monit . 2015 Nov; 21:3608-15. PMID: 26590375
Background: Alzheimer's disease (AD) is the most common type of dementia. It causes progressive brain disorder involving loss of normal memory and thinking skills. The transplantation of neural stem cells...
18.
Shi C, Luo X, Wang J, Long D
Steroids . 2015 Jan; 96:1-6. PMID: 25554578
It has been demonstrated that hypothalamus has a programmatic role in aging development, and this role of hypothalamus is mediated by nuclear factor-κB (NF-κB)-directed gonadotropin-releasing hormone (GnRH) decline. β-Sitosterol (BS),...
19.
Shi C, Zhu X, Wang J, Long D
J Bioenerg Biomembr . 2014 Jul; 46(5):371-6. PMID: 25052843
Mitochondrial dysfunction is a hallmark of amyloid β peptide (Aβ)-induced neuronal toxicity in Alzheimer's disease (AD). However, the underlying mechanism (s) of Aβ-induced mitochondrial dysfunction is still not fully understood....
20.
Liu F, Xuan A, Chen Y, Zhang J, Xu L, Yan Q, et al.
Mol Med Rep . 2014 Jul; 10(4):1739-45. PMID: 25051506
Neural stem cells (NSCs) are important pluripotent stem cells, which have potential applications in cell replacement therapy. Brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) have been demonstrated to...