Dagmar Wilhelm
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Explore the profile of Dagmar Wilhelm including associated specialties, affiliations and a list of published articles.
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81
Citations
3082
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Recent Articles
1.
Hatkevich T, Wilhelm D
Front Cell Dev Biol
. 2024 Dec;
12:1530367.
PMID: 39703695
No abstract available.
2.
Dinevska M, McAloney L, Widodo S, Filiz G, Anderson J, Dworkin S, et al.
Carcinogenesis
. 2024 Dec;
46(1).
PMID: 39672957
Testicular tumors are the most common malignancy of young men, and tumors affecting the testis are caused by somatic mutations in germ or germ-like cells. The PI3K pathway is constitutively...
3.
Bakhshalizadeh S, Bird A, Sreenivasan R, Bell K, Robevska G, van den Bergen J, et al.
Genes (Basel)
. 2024 Mar;
15(3).
PMID: 38540391
Disruption of meiosis and DNA repair genes is associated with female fertility disorders like premature ovarian insufficiency (POI). In this study, we identified a homozygous missense variant in the gene...
4.
5.
Rossitto M, Dejardin S, Rands C, Le Gras S, Migale R, Rafiee M, et al.
Nat Commun
. 2022 Jul;
13(1):4412.
PMID: 35906245
Gonadal sexual fate in mammals is determined during embryonic development and must be actively maintained in adulthood. In the mouse ovary, oestrogen receptors and FOXL2 protect ovarian granulosa cells from...
6.
Whatley E, Truong T, Wilhelm D, Harvey A, Gardner D
Hum Reprod
. 2022 Jul;
37(9):1994-2011.
PMID: 35856159
Study Question: What is the effect of the ketone β-hydroxybutyrate (βOHB) on preimplantation mouse embryo development, metabolism, epigenetics and post-transfer viability? Summary Answer: In vitro βOHB exposure at ketogenic diet...
7.
Mayere C, Regard V, Perea-Gomez A, Bunce C, Neirijnck Y, Djari C, et al.
Sci Adv
. 2022 May;
8(21):eabm0972.
PMID: 35613264
Gonadal sex determination represents a unique model for studying cell fate decisions. However, a complete understanding of the different cell lineages forming the developing testis and ovary remains elusive. Here,...
8.
Windley S, Mayere C, McGovern A, Harvey N, Nef S, Schwarz Q, et al.
Cell Death Dis
. 2022 Jan;
13(1):75.
PMID: 35075134
Gonadogenesis is the process wherein two morphologically distinct organs, the testis and the ovary, arise from a common precursor. In mammals, maleness is driven by the expression of Sry. SRY...
9.
Bagheri-Fam S, Combes A, Ling C, Wilhelm D
Hum Mol Genet
. 2020 Dec;
29(23):3781-3792.
PMID: 33305798
Heterozygous mutations in the human SOX9 gene cause the skeletal malformation syndrome campomelic dysplasia which in 75% of 46, XY individuals is associated with male-to-female sex reversal. Although studies in...
10.
Manning J, Windley S, Sandow J, Shah S, Western P, Wilhelm D, et al.
J Proteomics
. 2020 May;
223:103830.
PMID: 32450490
Posttranslational modification by ubiquitination targets proteins for degradation, recycling, stabilization or altered trafficking, and as such can alter cellular signaling pathways. The substrate specificity of this multistep process is controlled...