D W Jacobsen
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Explore the profile of D W Jacobsen including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Jacobsen D
Kidney Int
. 2006 Mar;
69(5):787-9.
PMID: 16518339
Hyperhomocysteinemia, an independent, modifiable risk factor for cardiovascular disease, is found in most patients with end-stage renal disease. In this issue, Perna et al. examine the extent of protein-S-linked and...
2.
Mizrahi E, Bowirrat A, Jacobsen D, Korczyn A, Traore F, Petot G, et al.
J Neurol Sci
. 2004 Nov;
227(1):109-13.
PMID: 15546600
High plasma homocysteine (tHcy) is a risk factor for cardiovascular disease and stroke and Alzheimer's disease (AD). An inverse relationship has been reported between tHcy and plasma B12 and folate...
3.
Mizrahi E, Jacobsen D, Debanne S, Traore F, Lerner A, Friedland R, et al.
J Nutr Health Aging
. 2003 May;
7(3):160-5.
PMID: 12766793
Purpose: To study the association between Alzheimer s disease (AD) and plasma total homocysteine (tHcy), dietary folate and vitamin B6. Methods: 64 AD patients were matched by gender, age, and...
4.
Rosolova H, Simon J, Mayer Jr O, Racek J, Dierze T, Jacobsen D
Physiol Res
. 2002 Jun;
51(1):93-8.
PMID: 12071296
Mild hyperhomocysteinemia has been established as a new independent risk factor for atherosclerosis and thrombosis. The metabolic syndrome of insulin resistance is associated with a high risk of coronary heart...
5.
Sengupta S, Wehbe C, Majors A, Ketterer M, Dibello P, Jacobsen D
J Biol Chem
. 2001 Oct;
276(50):46896-904.
PMID: 11592966
Disulfide forms of homocysteine account for >98% of total homocysteine in plasma from healthy individuals. We recently reported that homocysteine reacts with albumin-Cys(34)-S-S-cysteine to form homocysteine-cysteine mixed disulfide and albumin-Cys(34)...
6.
Budy B, Sengupta S, Dibello P, Kinter M, Jacobsen D
Anal Biochem
. 2001 Jun;
291(2):303-5.
PMID: 11401307
No abstract available.
7.
Poddar R, Sivasubramanian N, Dibello P, Robinson K, Jacobsen D
Circulation
. 2001 Jun;
103(22):2717-23.
PMID: 11390343
Background: Proinflammatory cytokines play key roles in atherogenesis and disease progression. Because hyperhomocysteinemia is an independent risk factor for cardiovascular disease, we hypothesized that homocysteine could be atherogenic by altering...
8.
Sengupta S, Chen H, Togawa T, Dibello P, Majors A, Budy B, et al.
J Biol Chem
. 2001 May;
276(32):30111-7.
PMID: 11371573
An elevated concentration of plasma total homocysteine is an independent risk factor for cardiovascular disease. Greater than 80% of circulating homocysteine is covalently bound to plasma protein by disulfide bonds....
9.
Dumaswala U, Zhuo L, Mahajan S, Nair P, Shertzer H, Dibello P, et al.
Am J Physiol Cell Physiol
. 2001 Mar;
280(4):C867-73.
PMID: 11245604
Oxidant stress, in vivo or in vitro, is known to induce oxidative changes in human red blood cells (RBCs). Our objective was to examine the effect of augmenting RBC glutathione...
10.
Togawa T, Sengupta S, Chen H, Robinson K, Nonevski I, Majors A, et al.
Biochem Biophys Res Commun
. 2000 Nov;
277(3):668-74.
PMID: 11062011
Hyperhomocysteinemia is an independent risk factor for cardiovascular disease. Greater than 70% of homocysteine in circulation is protein-bound. An in vitro model system using human plasma has been developed to...