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D Servent

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Articles 25
Citations 474
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Recent Articles
1.
Morais K, Ciccone L, Stura E, Alvarez-Flores M, Mourier G, Driessche M, et al.
Front Mol Biosci . 2023 Feb; 10:1072751. PMID: 36845546
Amblyomin-X is a Kunitz-type FXa inhibitor identified through the transcriptome analysis of the salivary gland from tick. This protein consists of two domains of equivalent size, triggers apoptosis in different...
2.
Maloney E, Taillebois E, Gilles N, Morrissey C, Liber K, Servent D, et al.
Aquat Toxicol . 2020 Nov; 230:105701. PMID: 33249296
Neonicotinoids are neuroactive insecticides commonly detected in freshwater ecosystems. Recent studies have indicated that these compounds are markedly toxic to Chironomidae, a widespread family of ecologically important aquatic insects. However,...
3.
Petrel C, Hocking H, Reynaud M, Upert G, Favreau P, Biass D, et al.
Biochem Pharmacol . 2013 Apr; 85(11):1663-71. PMID: 23567999
Conopeptides are a diverse array of small linear and reticulated peptides that interact with high potency and selectivity with a large diversity of receptors and ion channels. They are used...
4.
Quinton L, Girard E, Maiga A, Rekik M, Lluel P, Masuyer G, et al.
Br J Pharmacol . 2009 Dec; 159(2):316-25. PMID: 20015090
Background And Purpose: Venoms are a rich source of ligands for ion channels, but very little is known about their capacity to modulate G-protein coupled receptor (GPCR) activity. We developed...
5.
Paleari L, Catassi A, Ciarlo M, Cavalieri Z, Bruzzo C, Servent D, et al.
Cell Prolif . 2008 Dec; 41(6):936-59. PMID: 19040571
Objectives: Lung cancer is the most common cause of cancer death in the world. Cigarette smoking represents the major risk factor. Nicotine, an active component of cigarettes, can induce cell...
6.
Catassi A, Servent D, Paleari L, Cesario A, Russo P
Mutat Res . 2008 May; 659(3):221-31. PMID: 18495523
The genotoxic effects of tobacco carcinogens have long been recognized, the contribution of tobacco components to cancerogenesis by cell surface receptor signaling is relatively unexplored. Nicotine, the principal tobacco alkaloid,...
7.
Russo P, Catassi A, Cesario A, Servent D
Curr Med Chem . 2006 Dec; 13(29):3493-512. PMID: 17168719
One of the earliest descriptions of non-neuronal ACh synthesis was by Morris who reported that ACh was synthesized in the placenta [1]; furthermore, Falugi et al. showed the presence of...
8.
Picard F, Bruel D, Servent D, Saba W, Fruchart-Gaillard C, Schollhorn-Peyronneau M, et al.
Brain . 2006 Jul; 129(Pt 8):2047-60. PMID: 16815873
Nicotinic acetylcholine receptors (nAChRs) are involved in a familial form of frontal lobe epilepsy, autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE). In several ADNFLE families, mutations were identified in the...
9.
Gaillard C, Tamiya T, Corringer P, Changeux J, Servent D, Menez A
J Biol Chem . 2000 Jun; 275(38):29594-601. PMID: 10852927
Long chain curarimimetic toxins from snake venom bind with high affinities to both muscular type nicotinic acetylcholine receptors (AChRs) (K(d) in the pm range) and neuronal alpha 7-AChRs (K(d) in...
10.
Michalet S, Teixeira F, Gilquin B, Mourier G, Servent D, Drevet P, et al.
J Biol Chem . 2000 May; 275(33):25608-15. PMID: 10807914
We determined the distances separating five functionally important residues (Gln(10), Lys(27), Trp(29), Arg(33), and Lys(47)) of a three-fingered snake neurotoxin from the reduced disulfide bond alpha(Cys(192)-Cys(193)) located at the alphagamma...