D S Samuels
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Explore the profile of D S Samuels including associated specialties, affiliations and a list of published articles.
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32
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1169
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Recent Articles
11.
Cloud J, Marconi R, Eggers C, Garon C, Tilly K, Samuels D
Gene
. 1997 Jul;
194(1):137-41.
PMID: 9266683
The ATP-dependent protease Lon (La) of Escherichia coli degrades abnormal proteins and is involved in the regulation of capsular polysaccharide synthesis. In addition, mutations in the E. coli lon gene...
12.
Tilly K, Casjens S, Stevenson B, Bono J, Samuels D, Hogan D, et al.
Mol Microbiol
. 1997 Jul;
25(2):361-73.
PMID: 9282748
The 26 to 28kb circular plasmid of B. burgdorferi sensu lato (cp26) is ubiquitous among bacteria of this group and contains loci implicated in the mouse-tick transmission cycle. Restriction mapping...
13.
Hill S, Samuels D, Carlson J, Wilson J, Hogan D, Lubke L, et al.
Mol Microbiol
. 1997 Feb;
23(4):649-56.
PMID: 9157237
Integration host factor (IHF) is a small, heterodimeric DNA-binding protein with pleiotropic function. IHF was purified to apparent homogeneity from Neisseria gonorrhoeae. Gel-retardation assays demonstrated binding of IHF to the...
14.
Rosa P, Samuels D, Hogan D, Stevenson B, Casjens S, Tilly K
J Bacteriol
. 1996 Oct;
178(20):5946-53.
PMID: 8830691
Studies of the biology of Borrelia burgdorferi and the pathogenesis of Lyme disease are severely limited by the current lack of genetic tools. As an initial step toward facile genetic...
15.
Tilly K, Fuhrman J, Campbell J, Samuels D
Microbiology (Reading)
. 1996 Sep;
142 ( Pt 9):2471-9.
PMID: 8828214
Linear DNA with covalently closed ends is the predominant form of DNA in the spirochaete Borrelia burgdorferi. All bacteria examined to date have small DNA-binding proteins related to the Escherichia...
16.
Marconi R, Casjens S, Munderloh U, Samuels D
J Bacteriol
. 1996 Jun;
178(11):3357-61.
PMID: 8655522
The Borrelia genome is composed of a linear chromosome and a number of variable circular and linear plasmids. Atypically large linear plasmids of 92 to 105 kb have been identified...
17.
MARGOLIS N, Samuels D
Mol Biol Rep
. 1995 Jan;
21(3):159-64.
PMID: 8832904
The synthesis of the major outer surface proteins OspA and OspB in Borrelia burgdorferi varies among strains and during in vitro cultivation. We examined B. burgdorferi CA-11.2A for the presence...
18.
19.
Samuels D, Mach K, Garon C
J Bacteriol
. 1994 Oct;
176(19):6045-9.
PMID: 7928965
No useful method to genetically manipulate Borrelia burgdorferi, the causative agent of Lyme disease, has been developed previously. We have used resistance to the coumarin antibiotic coumermycin A1, an inhibitor...
20.
Samuels D, Shimizu Y, Nakabayashi T, Shimizu N
Biochim Biophys Acta
. 1994 Aug;
1223(1):77-83.
PMID: 8061056
DNA topoisomerase I is phosphorylated after mitogenic stimulation of 3T3-L1 mouse fibroblasts by 12-O-tetradecanoylphorbol 13-acetate (TPA), a phorbol ester tumor promoter. In vivo labeling with [32P]orthophosphate and immunoprecipitation with an...