D S Milstone
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Explore the profile of D S Milstone including associated specialties, affiliations and a list of published articles.
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22
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1518
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Recent Articles
1.
Duan S, Usher M, Foley 4th E, Milstone D, Brosius 3rd F, Mortensen R
Diabetologia
. 2010 Apr;
53(7):1493-505.
PMID: 20401461
Aims/hypothesis: The aim of this study was to determine the dependency on peroxisome proliferator-activated receptor-gamma (PPAR-gamma) of insulin sensitisation and glucose homeostasis by thiazolidinediones using a global Ppar-gamma (also known...
2.
Vernochet C, Milstone D, Iehle C, Belmonte N, Phillips B, Wdziekonski B, et al.
FEBS Lett
. 2002 Jan;
510(1-2):94-8.
PMID: 11755538
Peroxisome proliferator-activated receptor (PPAR) gamma was shown to be required for adipocyte formation both in vivo and in vitro. However, the role of PPARgamma in the initial steps of adipose...
3.
Jantzen H, Milstone D, Gousset L, Conley P, Mortensen R
J Clin Invest
. 2001 Aug;
108(3):477-83.
PMID: 11489941
The intracellular signaling pathways by which G protein-coupled receptors on the platelet surface initiate aggregation, a critical process for hemostasis and thrombosis, are not well understood. In particular, the contribution...
4.
Cybulsky M, Iiyama K, Li H, Zhu S, Chen M, Iiyama M, et al.
J Clin Invest
. 2001 May;
107(10):1255-62.
PMID: 11375415
VCAM-1 and ICAM-1 are endothelial adhesion molecules of the Ig gene superfamily that may participate in atherogenesis by promoting monocyte accumulation in the arterial intima. Both are expressed in regions...
5.
Jain M, Lim C, Nagata K, Davis V, Milstone D, Liao R, et al.
Am J Physiol Heart Circ Physiol
. 2001 Feb;
280(2):H569-75.
PMID: 11158953
Inhibitory Galpha(i) protein increases in the myocardium during hypertrophy and has been associated with beta-adrenergic receptor (beta-AR) desensitization, contractile dysfunction, and progression of cardiac disease. The role of Galpha(i) proteins...
6.
Moore K, Rosen E, Fitzgerald M, RANDOW F, Andersson L, Altshuler D, et al.
Nat Med
. 2001 Jan;
7(1):41-7.
PMID: 11135614
Peroxisome proliferator-activated receptor-gamma (PPAR-gamma), the transcription factor target of the anti-diabetic thiazolidinedione (TZD) drugs, is reported to mediate macrophage differentiation and inflammatory responses. Using PPAR-gamma-deficient stem cells, we demonstrate that...
7.
Nagata K, Ye C, Jain M, Milstone D, Liao R, Mortensen R
Circ Res
. 2000 Nov;
87(10):903-9.
PMID: 11073886
Parasympathetic stimulation of the heart acts through M(2)-muscarinic acetylcholine receptors to regulate ion channel activity and subsequent inotropic status. Although muscarinic signal transduction is mediated via pertussis toxin-sensitive G proteins...
8.
Milstone D, Redline R, ODonnell P, Davis V, Stavrakis G
Dev Dyn
. 2000 Sep;
219(1):63-76.
PMID: 10974672
Trophoblast are the earliest differentiated cells to emerge during mammalian ontogeny. Proper differentiation and maturation of trophoblast contributes to the fetal-maternal vascular interface of the mature placenta and is required...
9.
Milstone D, ODonnell P, Stavrakis G, Mortensen R, Davis V
Lab Invest
. 2000 Jul;
80(6):943-54.
PMID: 10879744
Leukocyte recruitment during inflammation is specified, in part, by the spatial distribution and temporal regulation of endothelial adhesion molecules. In this study we investigated the developmental onset of E-selectin and...
10.
Rosen E, Sarraf P, Troy A, Bradwin G, Moore K, Milstone D, et al.
Mol Cell
. 1999 Nov;
4(4):611-7.
PMID: 10549292
The process of adipogenesis is known to involve the interplay of several transcription factors. Activation of one of these factors, the nuclear hormone receptor PPAR gamma, is known to promote...