D R Soprano
Overview
Explore the profile of D R Soprano including associated specialties, affiliations and a list of published articles.
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Articles
77
Citations
733
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Recent Articles
1.
Patel J, Mehta J, Belosay A, Sabnis G, Khandelwal A, Brodie A, et al.
Br J Cancer
. 2007 Mar;
96(8):1204-15.
PMID: 17387344
Antitumour effects of retinoids are attributed to their influence on cell proliferation, differentiation, apoptosis and angiogenesis. In our effort to develop useful agents for breast cancer therapy, we evaluated the...
2.
Soprano K, Purev E, Vuocolo S, Soprano D
Oncogene
. 2006 Aug;
25(38):5315-25.
PMID: 16936753
Despite a number of attempts to improve treatment of ovarian cancer, it remains the most common cause of death from gynecological cancers. Thus, it is very important to identify more...
3.
Purev E, Soprano D, Soprano K
J Exp Clin Cancer Res
. 2004 Sep;
23(2):309-16.
PMID: 15354417
Vitamin A is an essential nutrient important for growth, vision, embryonic development, immune response and reproduction. Various retinoids have been shown to be effective chemotherapeutic and chemopreventive agents for a...
4.
Zhang D, Vuocolo S, Masciullo V, Sava T, Giordano A, Soprano D, et al.
Oncogene
. 2001 Dec;
20(55):7935-44.
PMID: 11753676
We have examined the effect of all-trans-retinoic acid (RA) on cell cycle gene expression in RA sensitive CA-OV3 and RA resistant SK-OV3 ovarian carcinoma cell lines. Gene expression was analysed...
5.
Kumar A, Soprano D, Parekh H
Cancer Res
. 2001 Oct;
61(20):7552-5.
PMID: 11606393
Treatment of ovarian carcinomas with the antimitotic antitumor drug paclitaxel is highly efficacious. However, development of drug resistance presents a major obstacle. The common cellular phenotypes associated with paclitaxel resistance...
6.
Soprano D, Gambone C, Sheikh S, Gabriel J, Chandraratna R, Soprano K, et al.
Toxicol Appl Pharmacol
. 2001 Jul;
174(2):153-9.
PMID: 11446831
The synthetic retinoid AGN 193109 is a potent pan retinoic acid receptor (RAR) antagonist. Treatment of pregnant mice with a single oral 1 mg/kg dose of this antagonist on day...
7.
Zhang D, Holmes W, Wu S, Soprano D, Soprano K
J Cell Physiol
. 2000 Aug;
185(1):1-20.
PMID: 10942515
Each year, an estimated 26,000 women in the United States are diagnosed with ovarian cancer. During any given year, approximately 14,500 women die from this disease. Ovarian cancer is the...
8.
Zhang Z, Shukri M, Gambone C, Gabriel J, Soprano K, Soprano D
Arch Biochem Biophys
. 2000 Aug;
380(2):339-46.
PMID: 10933889
The biological actions of retinoic acid (RA) are mediated by retinoic acid receptors (RARalpha, -beta, and -gamma) and retinoid X receptors (RXRalpha, -beta, and -gamma). Although the ligand-binding domains of...
9.
Soprano D, Scanlon E, Shukri M, Zhang Z, Soprano K
J Cell Biochem
. 2000 Apr;
77(4):604-14.
PMID: 10771516
The biological actions of retinoic acid (RA) are mediated by retinoic acid receptors (RARalpha, beta, and gamma) and retinoid X receptors (RXR alpha, beta, and gamma). Each of the RARs...
10.
Le Q, Dawson M, Soprano D, Soprano K
Oncogene
. 2000 Mar;
19(11):1457-65.
PMID: 10723137
Retinoids have been shown to inhibit the growth of many human tumor cells including breast, ovarian and squamous cell carcinoma (SCC). While the exact mechanism of retinoid mediated growth suppression...