D R Cundell
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Explore the profile of D R Cundell including associated specialties, affiliations and a list of published articles.
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22
Citations
713
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Recent Articles
1.
Cundell D, Silibovsky R, Sanders R, Sztandera L
Int J Med Inform
. 2001 Aug;
63(1-2):31-40.
PMID: 11518663
The initial diagnosis of bacterial infections in the absence of laboratory microbiological data requires physicians to use clinical algorithms based on symptoms, patient history and infection site. Optimization of such...
2.
Cundell D, Silibovsky R, Sanders R, Sztandera L
Artif Intell Med
. 2001 Jan;
21(1-3):235-9.
PMID: 11154891
Previous studies have suggested that the demographic variables of age and blood type may serve as "risk factors" for infection by specific bacterial species. Since both demographic variables and bacterial...
3.
Kanthakumar K, Taylor G, Cundell D, Dowling R, Johnson M, COLE P, et al.
Pulm Pharmacol
. 1996 Aug;
9(4):223-30.
PMID: 9160410
Toxins that slow ciliary beat are virulence determinants of bacteria that infect or invade ciliated epithelial surfaces. We have previously shown that the effect of the Pseudomonas aeruginosa toxin pyocyanin...
4.
Spellerberg B, Cundell D, Sandros J, Pearce B, Idanpaan-Heikkila I, Rosenow C, et al.
Mol Microbiol
. 1996 Feb;
19(4):803-13.
PMID: 8820650
Pneumococcus has been shown to bind to epithelial cells of the nasopharynx and lung, and to endothelial cells of the peripheral vasculature. To characterize bacterial elements required for attachment to...
5.
Cundell D, Gerard C, Idanpaan-Heikkila I, Tuomanen E, Gerard N
Adv Exp Med Biol
. 1996 Jan;
416:89-94.
PMID: 9131132
Streptococcus pneumoniae can produce asymptomatic colonization or aggressive sepsis. We sought to differentiate the molecular mechanisms of these disparate courses. Cytokine or thrombin activation of human vascular endothelial cells and...
6.
Garcia Rodriguez C, Cundell D, Tuomanen E, Kolakowski Jr L, Gerard C, Gerard N
J Biol Chem
. 1995 Oct;
270(42):25178-84.
PMID: 7559653
Streptococcus pneumoniae has been shown to utilize the platelet activating factor receptor for binding and invasion of host cells (Cundell, D. R., Gerard, N. P., Gerard, C., Idanpaan-Heikkila, I., and...
7.
Cundell D, Gerard N, Gerard C, Idanpaan-Heikkila I, Tuomanen E
Nature
. 1995 Oct;
377(6548):435-8.
PMID: 7566121
The Gram-positive bacterium Streptococcus pneumoniae is a major cause of pneumonia, sepsis and meningitis. Although the invasive disease is severe, some 40% of individuals harbour the pneumococcus in the nasopharynx...
8.
Cundell D, Pearce B, Sandros J, Naughton A, Masure H
Infect Immun
. 1995 Jul;
63(7):2493-8.
PMID: 7790061
To gain access to tissues within the human host, Streptococcus pneumoniae initially colonizes the nasopharynx and then interacts with glycoconjugates on the surfaces of target cells at various sites of...
9.
Cundell D, Weiser J, Shen J, Young A, Tuomanen E
Infect Immun
. 1995 Mar;
63(3):757-61.
PMID: 7868244
Phase variants in colonial opacity of pneumococci differ in the ability to colonize the nasopharynx of infant rats. To explain this observation at a cellular level, we compared the ability...
10.
Masure H, Campbell E, Cundell D, Pearce B, Sandros J, Spellerberg B
Dev Biol Stand
. 1995 Jan;
85:251-60.
PMID: 8586185
No abstract available.