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D R Bundle

Explore the profile of D R Bundle including associated specialties, affiliations and a list of published articles. Areas
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Articles 106
Citations 1345
Followers 0
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Recent Articles
1.
Nitz M, Bundle D
J Org Chem . 2001 Dec; 66(25):8411-23. PMID: 11735519
Homo oligomers of (1-->2)-beta-D-mannopyranosyl residues have been synthesized in order to study the unique immunological properties of the cell wall mannan of C. albicans. p-Chlorobenzyl-protected ulosyl bromide (2) in combination...
2.
Mulvey G, Kitov P, Marcato P, Bundle D, Armstrong G
Biochimie . 2001 Sep; 83(8):841-7. PMID: 11530217
The idea of using carbohydrate-based drugs to prevent attachment of microbial pathogens to host tissues has been around for about three decades. This concept evolved from the observation that many...
3.
Kitov P, Bundle D
Org Lett . 2001 Sep; 3(18):2835-8. PMID: 11529769
[reaction: see text]. A new one-pot method is described for the removal of O- and N-allyl protecting groups under oxidative conditions at near neutral pH. The allyl group undergoes hydroxylation...
4.
Ling C, Otter A, Bundle D
J Am Chem Soc . 2001 Jul; 123(18):4362-3. PMID: 11457214
No abstract available.
5.
Kitova E, Kitov P, Bundle D, Klassen J
Glycobiology . 2001 Jul; 11(7):605-11. PMID: 11447140
We show by nanoelectrospray ionization (nanoES) Fourier-transform ion cyclotron resonance mass spectrometry (FT-ICR MS) that it is possible to observe oligosaccharide-protein complexes with dissociation constants in the millimolar range, such...
6.
Nitz M, Purse B, Bundle D
Org Lett . 2000 Sep; 2(19):2939-42. PMID: 10986077
The synthesis of a portion of the challenging beta1,2-mannosyl polymer found in the cell walls of Candida albicans was undertaken to develop a conjugate vaccine against C. albicans and to...
7.
Nitz M, Bundle D
J Org Chem . 2000 May; 65(10):3064-73. PMID: 10814198
The synthesis of a linear trisaccharide epitope of the Trichinella spiralis N-linked glycan, in a form amenable to glycoconjugate formation, is reported. The trisaccharide contains the synthetically challenging LacdiNAc [beta-GalpNAc(1-->4)-beta-GlcpNAc]...
8.
Kitov P, Sadowska J, Mulvey G, Armstrong G, Ling H, Pannu N, et al.
Nature . 2000 Feb; 403(6770):669-72. PMID: 10688205
The diseases caused by Shiga and cholera toxins account for the loss of millions of lives each year. Both belong to the clinically significant subset of bacterial AB5 toxins consisting...
9.
Alexander J, del Guercio M, Maewal A, Qiao L, Fikes J, Chesnut R, et al.
J Immunol . 2000 Jan; 164(3):1625-33. PMID: 10640784
Linear carbohydrate-peptide constructs based on the 13 amino acid nonnatural pan DR epitope (PADRE) and carbohydrate B cell epitopes are demonstrated to be potent immunogens. These data support our belief...
10.
Young N, Gidney M, Gudmundsson B, MacKenzie C, To R, Watson D, et al.
Mol Immunol . 1999 Aug; 36(6):339-47. PMID: 10443998
The crystal structure of the complex of an anti-Id Fab with an Fab specific for a Brucella polysaccharide antigen has previously been reported (Evans et al., 1994, J. Mol. Biol....