D M Woodcock
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Explore the profile of D M Woodcock including associated specialties, affiliations and a list of published articles.
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43
Citations
766
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Recent Articles
1.
Woodcock D, Linsenmeyer M, Doherty J, Warren W
Br J Cancer
. 1999 Jan;
79(2):251-6.
PMID: 9888465
The p16 (CDKN2/MTS-1/INK4A) gene is one of several tumour-suppressor genes that have been shown to be inactivated by DNA methylation in various human cancers including breast tumours. We have used...
2.
Millward M, Webster L, Rischin D, Stokes K, Toner G, Bishop J, et al.
Clin Cancer Res
. 1998 Oct;
4(10):2321-9.
PMID: 9796961
Cremophor EL (cremophor), a component of the paclitaxel formulation, can potentially reverse P-glycoprotein-associated multidrug resistance. A Phase I trial of cremophor as a 6-h infusion every 3 weeks was performed...
3.
Woodcock D, Linsenmeyer M, Warren W
Gene
. 1998 Feb;
206(1):63-7.
PMID: 9461416
Mouse ES cells with a null mutation of the known DNA methyltransferase retain some residual DNA methylation and can methylate foreign sequences de novo. We have used bisulfite genomic sequencing...
4.
Woodcock D, Lawler C, Linsenmeyer M, Doherty J, Warren W
J Biol Chem
. 1997 Mar;
272(12):7810-6.
PMID: 9065445
We have investigated the function and sequence specificity of DNA methylation in the hypermethylated CpG island promoter region of the endogenous human LINE-1 (L1) retrotransposon family. In nontransformed human embryonic...
5.
Webster L, Linsenmeyer M, Rischin D, Urch M, Woodcock D, Millward M
Cancer Chemother Pharmacol
. 1997 Jan;
39(6):557-60.
PMID: 9118471
Docetaxel (Taxotere, Rhone-Poulenc Rorer) and etoposide are water-insoluble drugs formulated with polysorbate 80 for intravenous administration. We have previously reported that surfactants, including polysorbate 80 and Cremophor EL, can reverse...
6.
Du X, Vincan E, Woodcock D, Milano C, Dart A, Woodcock E
Am J Physiol
. 1996 Aug;
271(2 Pt 2):H630-6.
PMID: 8770105
Transgenic mice have been created with 200-fold overexpression of beta 2-adrenergic receptors specifically in the heart. Cardiac function was studied in these transgenic mice and their controls at baseline and...
7.
Woodcock D, Williamson M, Doherty J
Biochem Biophys Res Commun
. 1996 May;
222(2):460-5.
PMID: 8670227
A high background of read-through transcripts from degenerate human L1 retrotransposons is present in almost all human cell types. This prevents the detection of RNA transcripts from potentially functional elements....
8.
Littlejohn M, Camakaris J, Woodcock D
Somat Cell Mol Genet
. 1995 Nov;
21(6):385-98.
PMID: 8600567
We have isolated sites of de novo rearrangements from interspecific cell hybrids. Of 147,000 clones screened from a human/hamster hybrid genomic library, 14 clones were found with homology to both...
9.
Bertoncello I, Kriegler A, Woodcock D, Williams B, Barber L, Nilsson S
Int J Radiat Biol
. 1995 Jan;
67(1):57-64.
PMID: 7852817
The polyethoxylated castor oil, Cremophor EL (Cremophor) is approved for human use as a vehicle for oral and intravenous administration of water-insoluble compounds. Cremophor has also previously been shown to...
10.
Woodcock E, LAND S, Andrews R, Linsenmeyer M, Woodcock D
Biochem J
. 1994 Nov;
304 ( Pt 1):113-9.
PMID: 7998921
Endothelin receptors with endothelin-A (ETa) specificity were present in neonatal rat ventricle. However, in both receptor-binding studies and studies of inositol phosphate accumulation, these receptors had lower affinity for endothelin-1...