D Lavelle
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Explore the profile of D Lavelle including associated specialties, affiliations and a list of published articles.
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19
Citations
251
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Recent Articles
1.
Tannu S, Renzetti L, Tare N, Ventre J, Lavelle D, Lin T, et al.
Br J Pharmacol
. 2010 Aug;
161(6):1329-42.
PMID: 20735404
Background And Purpose: Vasoactive intestinal peptide is expressed in the respiratory tract and induces its effects via its receptors, VPAC(1) and VPAC(2). RO5024118 is a selective VPAC(2) receptor agonist derived...
2.
Truco M, Antonise R, Lavelle D, Ochoa O, Kozik A, Witsenboer H, et al.
Theor Appl Genet
. 2007 Sep;
115(6):735-46.
PMID: 17828385
An integrated map for lettuce comprising of 2,744 markers was developed from seven intra- and inter-specific mapping populations. A total of 560 markers that segregated in two or more populations...
3.
Lavelle D, Chen Y, Hankewych M, DESIMONE J
Am J Hematol
. 2002 Jan;
68(3):170-8.
PMID: 11754398
Histone deacetylase (HDAC) inhibitors cause growth arrest and apoptosis of cancer cells by both p21-dependent and independent mechanisms. Decreased expression of growth factor receptors may be a key factor in...
4.
Lavelle D, Molokie R, Ducksworth J, DESIMONE J
Exp Hematol
. 2001 Feb;
29(2):156-62.
PMID: 11166454
Objective: Augmentation of the level of fetal hemoglobin (HbF) is considered therapeutic for patients with sickle cell disease. The objective of this study was to determine the effect of treatment...
5.
Koshy M, Dorn L, Bressler L, Molokie R, Lavelle D, Talischy N, et al.
Blood
. 2000 Sep;
96(7):2379-84.
PMID: 11001887
Augmentation of the fetal hemoglobin (HbF) levels is of therapeutic benefit in patients with sickle cell anemia. Hydroxyurea (HU), by increasing HbF, lowers rates of pain crisis, episodes of acute...
6.
Lavelle D, Chen Y, Hankewych M, DESIMONE J
Leuk Lymphoma
. 2000 Mar;
35(3-4):261-8.
PMID: 10706449
Retinoic acid and dexamethasone, in combination, inhibit the growth of human myeloma cell lines in a synergistic manner. Previously, we observed that all-trans retinoic acid (ATRA) caused G1 arrest and...
7.
Chen Y, Lavelle D, DESIMONE J, Uddin S, Platanias L, Hankewych M
Blood
. 1999 Jun;
94(1):251-9.
PMID: 10381520
All-trans retinoic acid (ATRA) has previously been shown to inhibit the growth of OPM-2 human myeloma cells. The growth inhibition was postulated to result from a transcriptional downregulation of interleukin-6...
8.
Chen Y, Shiao R, Labayog J, Modi S, Lavelle D
Leuk Lymphoma
. 1997 Dec;
27(1-2):11-23.
PMID: 9373192
Interluekin-6 (IL-6)/IL-6 receptor (IL-6R) play a major role in autocrine/paracrine growth regulation of myeloma cells and are the central mediators for bone destruction and other systemic manifestations of multiple myeloma....
9.
Chen Y, Desai P, Shiao R, Lavelle D, Haleem A, Chen J
Blood
. 1996 Jan;
87(1):314-23.
PMID: 8547658
Interleukin-6 (IL-6)/IL-6 receptor (IL-6R) plays a major role in autocrine/paracrine growth regulation of myeloma cells. We investigated the effect of dexamethasone and all-trans retinoic acid, previously shown to modulate IL-6/IL-6R,...
10.
Sengupta P, Lavelle D, DESIMONE J
Am J Hematol
. 1994 Jul;
46(3):169-72.
PMID: 8192145
We have studied the effect of site-specific cytosine methylation on the binding of nuclear proteins to the gamma-globin promoter region from -71 to -34. This sequence was recently shown to...