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D L St Germain

Explore the profile of D L St Germain including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 830
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Recent Articles
1.
Ward T, St Germain D, Comi R, Cromwell L
Cephalalgia . 2002 Mar; 21(9):921-3. PMID: 11903288
No abstract available.
2.
Schneider M, Fiering S, Pallud S, Parlow A, St Germain D, Galton V
Mol Endocrinol . 2001 Dec; 15(12):2137-48. PMID: 11731615
The type 2 deiodinase (D2), a selenoenzyme that catalyzes the conversion of T4 to T3 via 5'-deiodination, is expressed in the pituitary, brain, brown adipose tissue (BAT), and the reproductive...
3.
Galton V, Martinez E, Hernandez A, St Germain E, Bates J, St Germain D
Endocrinology . 2001 Apr; 142(5):2123-8. PMID: 11316780
Thyroid hormones are of considerable importance for vertebrate reproductive function and during development. To further assess the role of these compounds in this capacity, we examined the expression pattern of...
4.
Wu S, Huang W, Fisher D, FLORSHEIM W, St Germain D, Galton V
Pediatr Res . 2000 Dec; 48(6):847-51. PMID: 11102557
In developing mammals, we and others demonstrated that sulfation is an important pathway in the metabolism of thyroid hormone, and there is significant fetal-maternal transfer of sulfated iodothyronine. In the...
5.
Bates J, Spate V, Morris J, St Germain D, Galton V
Endocrinology . 2000 Jun; 141(7):2490-500. PMID: 10875250
The iodothyronine deiodinases, D1, D2, and D3, all contain selenium (Se) in the form of selenocysteine at their active sites, and they play crucial roles in determining the circulating and...
6.
Pallud S, Ramauge M, Gavaret J, Lennon A, MUNSCH N, St Germain D, et al.
Endocrinology . 1999 May; 140(6):2917-23. PMID: 10342885
The type 3 iodothyronine deiodinase (D3) metabolizes thyroid hormones to inactive metabolites in many tissues, including the brain. In the present studies, we have examined the mechanisms by which T3...
7.
Galton V, Martinez E, Hernandez A, St Germain E, Bates J, St Germain D
J Clin Invest . 1999 Apr; 103(7):979-87. PMID: 10194470
Although thyroid hormones are critically important for the coordination of morphogenic processes in the fetus and neonate, premature exposure of the embryo to levels of the hormones present in the...
8.
St Germain D
Biochem Soc Trans . 1999 Mar; 27(2):83-8. PMID: 10093712
No abstract available.
9.
Bates J, St Germain D, Galton V
Endocrinology . 1999 Feb; 140(2):844-51. PMID: 9927314
Thyroid hormone (TH) is essential for normal development in vertebrate species. Although the mechanisms by which TH regulates developmental processes are not fully understood, intracellular T3 levels are likely to...
10.
Hernandez A, Lyon G, Schneider M, St Germain D
Endocrinology . 1999 Jan; 140(1):124-30. PMID: 9886816
The type 3 iodothyronine deiodinase (D3) is a selenoenzyme that inactivates thyroid hormones by removing a iodine from the 5-position of the tyrosyl ring. D3 is highly expressed in many...