D L Patton
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Explore the profile of D L Patton including associated specialties, affiliations and a list of published articles.
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78
Citations
1549
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Recent Articles
1.
Hashway S, Bergin I, Bassis C, Uchihashi M, Schmidt K, Young V, et al.
J Med Primatol
. 2013 Nov;
43(2):89-99.
PMID: 24266633
Background: Use of a levonorgestrel-releasing intrauterine system (LNG-IUS) in humans may alter vaginal microbial populations and susceptibility to pathogens. This study evaluated the time-dependent effects of an LNG-IUS on the...
2.
Bergin I, Bell J, Chen Z, Zochowski M, Chai D, Schmidt K, et al.
Vet Pathol
. 2012 Mar;
50(1):200-8.
PMID: 22446324
Genital Alphapapillomavirus (αPV) infections are one of the most common sexually transmitted human infections worldwide. Women infected with the highly oncogenic genital human papillomavirus (HPV) types 16 and 18 are...
3.
Sassi A, Cost M, Cole A, Cole A, Patton D, Gupta P, et al.
Antimicrob Agents Chemother
. 2011 Feb;
55(5):2282-9.
PMID: 21321138
RC-101 is a synthetic microbicide analog of retrocyclin, which has shown in vitro activity against X4 and R5 HIV-1. In an effort to develop a safe and effective RC-101 vaginal...
4.
Patton D, Sweeney Y, Balkus J, Rohan L, Moncla B, Parniak M, et al.
Antimicrob Agents Chemother
. 2007 Mar;
51(5):1608-15.
PMID: 17353240
The nonnucleoside reverse transcriptase inhibitor UC781 is under development as a potential microbicide to prevent sexual transmission of human immunodeficiency virus type 1 (HIV-1). Two gel formulations of UC781 (0.1%...
5.
Patton D, Sweeney Y, McCarthy T, Hillier S
Antimicrob Agents Chemother
. 2006 Apr;
50(5):1696-700.
PMID: 16641437
Three gel formulations (1%, 3%, and 5% [wt/wt]) of SPL7013, a dendrimer known to have antiviral (anti-human immunodeficiency virus and anti-herpes simplex virus) activities, completed a range of preclinical tests...
6.
Patton D, Sweeney Y, Cummings P, Meyn L, Rabe L, Hillier S
Sex Transm Dis
. 2004 Apr;
31(5):290-6.
PMID: 15107631
Background: The nonhuman primate model allows for safety and efficacy testing of topical microbicide products. Goal: The goal of this study was to evaluate the safety and efficacy of vaginal...
7.
Patton D, Cosgrove-Sweeney Y, Rabe L, Hillier S
Sex Transm Dis
. 2001 Jul;
28(7):363-6.
PMID: 11460018
Background: A topical microbicide should protect against acquisition of sexually transmitted infection during both vaginal and rectal intercourse. The rectal microflora of the Macaca nemestrina (pig-tailed macaque) and humans were...
8.
Eschenbach D, Patton D, Hooton T, Meier A, Stapleton A, Aura J, et al.
J Infect Dis
. 2001 Mar;
183(6):913-8.
PMID: 11237808
Effects of a single episode of intercourse on vaginal flora and epithelium were examined in subjects randomly assigned to groups that used no condom or lubricated nonspermicide condoms. Subjects were...
9.
Eschenbach D, Patton D, Meier A, Thwin S, Aura J, Stapleton A, et al.
Contraception
. 2000 Dec;
62(3):107-12.
PMID: 11124356
The objective of this study was to examine the effect of oral contraceptive (OC) use on vaginal discharge, epithelium, and flora. Thirty women who planned to use OC for contraception...
10.
Patton D, Thwin S, Meier A, Hooton T, Stapleton A, Eschenbach D
Am J Obstet Gynecol
. 2000 Oct;
183(4):967-73.
PMID: 11035348
Objective: The aim of our study was to examine vaginal tissue during 3 phases of the menstrual cycle for the number of cell layers and epithelial immune cells. Study Design:...