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D L Patton

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Articles 78
Citations 1549
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Recent Articles
11.
Miller L, Patton D, Meier A, Thwin S, Hooton T, Eschenbach D
Obstet Gynecol . 2000 Aug; 96(3):431-9. PMID: 10960638
Objective: To identify the effects of depomedroxyprogesterone acetate (DMPA) on vaginal microbial flora and epithelium. Methods: Women who desired DMPA for contraception were evaluated before and at 3 and 6...
12.
Lichtenwalner A, Patton D, Klebanoff S, Headley C, Hillier S
J Med Primatol . 2000 Jun; 29(1):36-41. PMID: 10870673
Myeloperoxidase (MPO) is an enzyme in neutrophils and monocytes which reacts with H2O2 and chloride to kill microbes after phagocytosis. Instillation of MPO into the vagina may augment vaginal defenses...
13.
Eschenbach D, Thwin S, Patton D, Hooton T, Stapleton A, Agnew K, et al.
Clin Infect Dis . 2000 Jun; 30(6):901-7. PMID: 10852812
The objective of this study was to examine genital tissue, vaginal fluid, and vaginal microbial flora at 3 phases of the menstrual cycle in asymptomatic women. Vaginal examinations were performed...
14.
Toth M, Patton D, Campbell L, Carretta E, Mouradian J, Toth A, et al.
Am J Reprod Immunol . 2000 Jun; 43(4):218-22. PMID: 10836251
Problem: The pathogenesis of long-term sequelae in Chlamydia trachomatis infection is poorly understood. While serology indicates previous chlamydial infection, culture studies are frequently negative. We wanted to know whether in...
15.
Peeling R, Patton D, Sweeney Y, Cheang M, Lichtenwalner A, Brunham R, et al.
J Infect Dis . 1999 Aug; 180(3):774-9. PMID: 10438366
A primate model of chlamydial pelvic inflammatory disease was used to characterize serum antibody responses to the 60 kDa chlamydial heat shock protein (CHSP60). Forty monkeys were infected in the...
16.
Patton D, Kidder G, Sweeney Y, Rabe L, Hillier S
Am J Obstet Gynecol . 1999 May; 180(5):1080-7. PMID: 10329859
Objective: Safe and effective vaginally applied microbicides could help to control the continuing spread of sexually transmitted diseases. Study Design: This study used nonhuman primates to test the effects of...
17.
Leng Z, Moore D, Mueller B, Critchlow C, Patton D, Halbert S, et al.
Hum Reprod . 1998 Dec; 13(11):3121-7. PMID: 9853868
Biopsy specimens were obtained from the distal end of the Fallopian tubes of 62 women with tubal infertility and examined by light and electron microscopy. Ciliary beat frequency (CBF) measurements...
18.
Patton D, Sweeney Y, McKay T, DeMers S, Clark A, Rabe L, et al.
Sex Transm Dis . 1998 Oct; 25(8):421-4. PMID: 9773435
Background And Objectives: An estimated 4 million new cases of chlamydial infection occur each year. This experiment assessed the effects of a vaginally applied gel formulation of 0.25% chlorhexidine gluconate...
19.
Lampe M, Ballweber L, Isaacs C, Patton D, Stamm W
Antimicrob Agents Chemother . 1998 May; 42(5):1239-44. PMID: 9593157
The development of new methods for prevention of sexually transmitted Chlamydia trachomatis infection is a top public health priority. Topical self-administered vaginal microbicides represent one such approach in which the...
20.
Roos T, Martin T, Ruzinski J, Leturcq D, Hillier S, Patton D, et al.
Am J Obstet Gynecol . 1997 Dec; 177(5):1230-7. PMID: 9396923
Objectives: Our purpose was to examine whether lipopolysaccharide binding protein and soluble CD14 are present in amniotic fluid and to determine whether the lipopolysaccharide binding protein and soluble CD14 concentrations...