D L Hachey
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Explore the profile of D L Hachey including associated specialties, affiliations and a list of published articles.
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65
Citations
718
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Recent Articles
1.
Stamer W, Hoffman E, Luther J, Hachey D, Schey K
J Proteomics
. 2011 Mar;
74(6):796-804.
PMID: 21362503
To better understand the role of exosomes in the trabecular meshwork (TM), the site of intraocular pressure control, the exosome proteome from primary cultures of human TM cell monolayers was...
2.
Hoogeveen R, Ballantyne C, Pownall H, Opekun A, Hachey D, Jaffe J, et al.
Transplantation
. 2001 Oct;
72(7):1244-50.
PMID: 11602850
Background: Sirolimus (Rapamune, rapamycin, RAPA) is a potent immunosuppressive drug that has reduced the rate of acute rejection episodes by more than 40% in phase III trials when added to...
3.
Yin H, Hachey D, Porter N
J Am Soc Mass Spectrom
. 2001 Apr;
12(4):449-55.
PMID: 11322191
Organic peroxides have significance in organic synthesis and biological processes. Characterization of these compounds with weak O-O bonds is sometimes difficult due to their thermal instability and sensitivity to acid...
4.
Murphey L, Hachey D, Vaughan D, Brown N, Morrow J
Anal Biochem
. 2001 Apr;
292(1):87-93.
PMID: 11319821
Bradykinin is a vasoactive nonapeptide involved in cardiorenal physiology and inflammatory states. It has been linked to the pathophysiology of hypertension and diabetes. Correlating levels of bradykinin with disease states...
5.
Neocytolysis on descent from altitude: a newly recognized mechanism for the control of red cell mass
Rice L, Ruiz W, Driscoll T, Whitley C, Tapia R, Hachey D, et al.
Ann Intern Med
. 2001 Apr;
134(8):652-6.
PMID: 11304105
Background: Studies of space-flight anemia have uncovered a physiologic process, neocytolysis, by which young red blood cells are selectively hemolyzed, allowing rapid adaptation when red cell mass is excessive for...
6.
Li Z, Kaplan M, Hachey D
Lipids
. 2001 Feb;
35(12):1325-33.
PMID: 11201994
The roles of peroxisomes and microsomes on the biosynthetic pathway for docosahexaenoic acid (DHA) from alpha-linolenic acid (ALA) were investigated. Microsomes and peroxisomes were prepared from livers of fetal and...
7.
Organization, management and operation of contemporary academic mass spectrometry service facilities
Wood K, Hachey D
J Mass Spectrom
. 2000 Dec;
35(10):1157-64.
PMID: 11110088
The rapid evolution of mass spectrometry in the past 15 years has moved mass spectrometry facilities from the traditional model in which instruments were located in and used for a...
8.
He H, Sadeque A, Erve J, Wood A, Hachey D
J Chromatogr B Biomed Sci Appl
. 2000 Sep;
744(2):323-31.
PMID: 10993521
We report here the development and validation of an LC-MS method for quantitation of loperamide (LOP) and its N-demethyl metabolite (DMLOP) in human plasma. O-Acetyl-loperamide (A-LOP) was synthesized by us...
9.
Yin H, Hachey D, Porter N
Rapid Commun Mass Spectrom
. 2000 Aug;
14(14):1248-54.
PMID: 10918375
Organic peroxides have significant implications in organic chemistry and biological processes. The weak O-O bond makes them extremely difficult to characterize by conventional analytical methods. Diacyl peroxides are one of...
10.
Murphey L, Hachey D, OATES J, Morrow J, Brown N
J Pharmacol Exp Ther
. 2000 Jun;
294(1):263-9.
PMID: 10871321
Studies investigating the role of bradykinin in disease states such as hypertension, sepsis, and asthma have been confounded by difficulties in measuring the concentration of this short-lived peptide. The purpose...