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D J Watt

Explore the profile of D J Watt including associated specialties, affiliations and a list of published articles. Areas
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Articles 34
Citations 598
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Recent Articles
1.
Blackburn S, Wood C, Evans D, Watt D
Clin Anat . 2005 Nov; 20(1):64-7. PMID: 16302241
The midline of the brachialis muscle is now regarded by many surgeons as an internervous plane, between the musculocutaneous nerve supply to the medial portion and a radial nerve contribution...
2.
Goldring K, Jones G, Sewry C, Watt D
Neuromuscul Disord . 2001 Dec; 12(2):183-6. PMID: 11738361
We have previously shown that galectin-1 is a factor capable of converting mouse dermal fibroblasts to the myogenic lineage [Cell Transplant 2000;9:519]. Here, we report that human dermal fibroblasts are...
3.
Pye D, Watt D
J Anat . 2001 Mar; 198(Pt 2):163-73. PMID: 11273041
Both in vitro and in vivo studies have described the conversion of fibroblasts to myogenesis when in the presence of dysfunctional myogenic cells. Myogenic conversion of fibroblasts subjected to a...
4.
Goldring K, Jones G, Watt D
Cell Transplant . 2000 Oct; 9(4):519-29. PMID: 11038068
Using the mdx mouse model for human Duchenne muscular dystrophy we have shown that a cell population residing in the dermis of C57B1/10ScSn mouse skin is capable of converting to...
5.
Eriksson M, Ansved T, Edstrom L, Wells D, Watt D, Anvret M, et al.
J Biol Chem . 2000 Apr; 275(26):19964-9. PMID: 10748037
Myotonic dystrophy is caused by a CTG(n) expansion in the 3'-untranslated region of a serine/threonine protein kinase gene (DMPK), which is flanked by two other genes, DMWD and SIX5. One...
6.
Skynner M, Drage D, Dean W, Turner S, Watt D, Allen N
Int J Dev Biol . 1999 Apr; 43(1):85-90. PMID: 10213086
A fundamental keystone of developmental biology has been the growing use of reporter genes in model transgenic systems. Their use has greatly facilitated investigations of cell lineage and cell fate...
7.
Clark K, Watt D, Lightowlers R, Johnson M, Relvas J, Taanman J, et al.
J Clin Invest . 1998 Dec; 102(12):2090-5. PMID: 9854044
Defects of the mitochondrial genome are important causes of disease. Despite major advances in our investigation of patients, there is no effective therapy. Progress in this area is limited by...
8.
Okoli G, Carey N, Johnson K, Watt D
Biochem Biophys Res Commun . 1998 Jun; 246(3):905-11. PMID: 9618310
Myotonic dystrophy (DM) is an autosomal dominant human disorder, caused by the abnormal expansion of a CTG trinucleotide repeat in the 3' untranslated region of a protein kinase gene (DMPK)....
9.
Sewry C, Uziyel Y, Torelli S, Buchanan S, Sorokin L, Cohen J, et al.
Neuropathol Appl Neurobiol . 1998 Apr; 24(1):66-72. PMID: 9549731
Laminin alpha 2, a sub-unit of the basement membrane component laminin-2, is deficient in the dy/dy and allelic dy2 J/dy2 J mouse. It is also the defective protein in a...
10.
Deconinck A, Rafael J, Skinner J, Brown S, Potter A, METZINGER L, et al.
Cell . 1997 Aug; 90(4):717-27. PMID: 9288751
The absence of dystrophin at the muscle membrane leads to Duchenne muscular dystrophy (DMD), a severe muscle-wasting disease that is inevitably fatal in early adulthood. In contrast, dystrophin-deficient mdx mice...