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D J Kelleher

Explore the profile of D J Kelleher including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 520
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Recent Articles
1.
Karaoglu D, Kelleher D, Gilmore R
Biochemistry . 2001 Oct; 40(40):12193-206. PMID: 11580295
The oligosaccharyltransferase (OST) preferentially utilizes the fully assembled dolichol-linked oligosaccharide Glc(3)Man(9)GlcNAc(2)-PP-Dol as the donor for N-linked glycosylation of asparagine residues in N-X-T/S consensus sites in newly synthesized proteins. A wide...
2.
Kelleher D, Karaoglu D, Gilmore R
Glycobiology . 2001 May; 11(4):321-33. PMID: 11358881
The dolichol-linked oligosaccharide donor (Glc(3)Man(9)GlcNAc(2)-PP-Dol) for N-linked glycosylation of proteins is assembled in a series of reactions that initiate on the cytoplasmic face of the rough endoplasmic reticulum and terminate...
3.
Karaoglu D, Kelleher D, Gilmore R
J Biol Chem . 1998 Jan; 272(51):32513-20. PMID: 9405463
The oligosaccharyltransferase has been purified from Saccharomyces cerevisiae as an hetero-oligomeric complex composed of four or six subunits. Here, the in vivo subunit composition and stoichiometry of the oligosaccharyltransferase were...
4.
Kelleher D, Gilmore R
Proc Natl Acad Sci U S A . 1997 May; 94(10):4994-9. PMID: 9144178
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the BHK21-derived tsBN7 cell line. Of interest, the 12.5-kDa DAD1 protein...
5.
Silberstein S, COLLINS P, Kelleher D, Gilmore R
J Cell Biol . 1995 Oct; 131(2):371-83. PMID: 7593165
Oligosaccharyltransferase catalyzes the transfer of a preassembled high mannose oligosaccharide from a dolichol-oligosaccharide donor to consensus glycosylation acceptor sites in newly synthesized proteins in the lumen of the rough endoplasmic...
6.
Karaoglu D, Kelleher D, Gilmore R
J Cell Biol . 1995 Aug; 130(3):567-77. PMID: 7622558
Within the lumen of the rough endoplasmic reticulum, oligosaccharyltransferase catalyzes the en bloc transfer of a high mannose oligosaccharide moiety from the lipid-linked oligosaccharide donor to asparagine acceptor sites in...
7.
Silberstein S, COLLINS P, Kelleher D, Rapiejko P, Gilmore R
J Cell Biol . 1995 Feb; 128(4):525-36. PMID: 7860628
Oligosaccharyltransferase mediates the transfer of a preassembled high mannose oligosaccharide from a lipid-linked oligosaccharide donor to consensus glycosylation acceptor sites in newly synthesized proteins in the lumen of the rough...
8.
Noy N, Kelleher D, Scotto A
J Lipid Res . 1995 Feb; 36(2):375-82. PMID: 7751826
The interactions of retinol with vesicles of dioleoylphosphatidylcholine of varying radii were studied. The rate constants of dissociation of retinol from bilayers (k(off)) and the equilibrium partition constants (Keq) of...
9.
Karaoglu D, Silberstein S, Kelleher D, Gilmore R
Cold Spring Harb Symp Quant Biol . 1995 Jan; 60:83-92. PMID: 8824380
No abstract available.
10.
Kelleher D, Gilmore R
J Biol Chem . 1994 Apr; 269(17):12908-17. PMID: 8175708
Asparagine-linked glycosylation of proteins in the lumen of the endoplasmic reticulum is catalyzed by the oligosaccharyltransferase. Previously, the mammalian oligosaccharyltransferase was shown to co-purify with a protein complex consisting of...