D J Drucker
Overview
Explore the profile of D J Drucker including associated specialties, affiliations and a list of published articles.
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Articles
135
Citations
4828
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Recent Articles
11.
KOEHLER J, Yusta B, Drucker D
Mol Endocrinol
. 2004 Oct;
19(2):459-73.
PMID: 15471943
Glucagon-like peptide-2 (GLP-2) regulates proliferative and cytoprotective pathways in the intestine; however GLP-2 receptor (GLP-2R) signal transduction remains poorly understood, and cell lines that express the endogenous GLP-2R have not...
12.
Yusta B, Drucker D
Journ Annu Diabetol Hotel Dieu
. 2004 Jul;
:127-37.
PMID: 15259311
No abstract available.
13.
Hansotia T, Baggio L, Delmeire D, Hinke S, Yamada Y, Tsukiyama K, et al.
Diabetes
. 2004 Apr;
53(5):1326-35.
PMID: 15111503
Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 (GLP-1) are gut-derived incretins that potentiate glucose clearance following nutrient ingestion. Elimination of incretin receptor action in GIPR(-/-) or GLP-1R(-/-) mice produces...
14.
Lovshin J, Huang Q, Seaberg R, Brubaker P, Drucker D
Endocrinology
. 2004 Apr;
145(7):3495-506.
PMID: 15059959
Proglucagon-derived glucagon-like peptide-2 (GLP-2) is liberated in enteroendocrine cells and neurons. GLP-2 regulates energy absorption and epithelial integrity in the gastrointestinal tract, whereas GLP-2 action in the central nervous system...
15.
Brubaker P, Drucker D
Endocrinology
. 2004 Mar;
145(6):2653-9.
PMID: 15044356
Gut peptides exert diverse effects regulating satiety, gastrointestinal motility and acid secretion, epithelial integrity, and both nutrient absorption and disposal. These actions are initiated by activation of specific G protein-coupled...
16.
Lovshin J, Drucker D
Pediatr Diabetes
. 2004 Mar;
1(1):49-57.
PMID: 15016242
Glucagon-like peptides-1 and -2 (GLP-1 and GLP-2) are co-encoded along with glucagon in a single mammalian proglucagon gene that is expressed in islets and enteroendocrine L cells of the small...
17.
Brubaker P, Drucker D
Recept Channels
. 2003 Jan;
8(3-4):179-88.
PMID: 12529935
The glucagon-like peptides include glucagon, GLP-1, and GLP-2, and exert diverse actions on nutrient intake, gastrointestinal motility, islet hormone secretion, cell proliferation and apoptosis, nutrient absorption, and nutrient assimilation. GIP,...
18.
Adatia F, Baggio L, Xiao Q, Drucker D, Brubaker P
Endocrinology
. 2002 Aug;
143(9):3464-71.
PMID: 12193559
Glucagon-like peptide-1 (GLP-1) is a potent stimulator of glucose-dependent insulin secretion. Exendin-4(1-39) (Ex-4), isolated from Gila monster venom, is a highly specific GLP-1 receptor agonist that exhibits a prolonged duration...
19.
Drucker D
Gut
. 2002 Feb;
50(3):428-35.
PMID: 11839727
The glucagon-like peptides GLP-1 and GLP-2 are synthesised and then released from enteroendocrine cells in the small and large intestine. GLP-1 promotes efficient nutrient assimilation while GLP-2 regulates energy absorption...
20.
Drucker D
Curr Pharm Des
. 2001 Jul;
7(14):1399-412.
PMID: 11472275
Glucagon-like peptide-1 (GLP-1) is released from gut endocrine cells following nutrient ingestion and acts to regulate nutrient assimilation via effects on gastrointestinal motility, islet hormone secretion, and islet cell proliferation....