D J Christensen
Overview
Explore the profile of D J Christensen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
17
Citations
461
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Pippa R, Dominguez A, Christensen D, Moreno-Miralles I, Blanco-Prieto M, Vitek M, et al.
Leukemia
. 2014 May;
28(9):1915-8.
PMID: 24781014
No abstract available.
2.
Vitek M, Christensen D, Wilcock D, Davis J, Van Nostrand W, Li F, et al.
Neurodegener Dis
. 2012 Feb;
10(1-4):122-6.
PMID: 22326991
Background: After age, the second largest risk factor for Alzheimer's disease (AD) is apolipoprotein E (APOE) genotype, where APOE4 is associated with lower apoE protein levels, more severer brain pathology,...
3.
Switzer C, Cheng R, Vitek T, Christensen D, Wink D, Vitek M
Oncogene
. 2011 Feb;
30(22):2504-13.
PMID: 21297667
The SET oncoprotein participates in cancer progression by affecting multiple cellular processes, inhibiting the tumor suppressor protein phosphatase 2A (PP2A), and inhibiting the metastasis suppressor nm23-H1. On the basis of...
4.
APOE genotype affects outcome in a murine model of sepsis: implications for a new treatment strategy
Wang H, Christensen D, Vitek M, Sullivan P, Laskowitz D
Anaesth Intensive Care
. 2009 Jan;
37(1):38-45.
PMID: 19157344
In this study, we assessed whether apolipoprotein E (APOE) polymorphism affects inflammatory responses and mortality in the caecal ligation and puncture model of peritonitis. In addition, we determined the effects...
5.
Christensen D, Gottlin E, BENSON R, Hamilton P
Drug Discov Today
. 2001 Jul;
6(14):721-727.
PMID: 11445463
Increasing bacterial drug resistance and hard-to-eradicate opportunistic infections have created a need for new antibiotics. Sequencing of microbial genomes has yielded many new potential targets for antibacterial drug discovery. However,...
6.
Hyde-DeRuyscher R, Paige L, Christensen D, Lim A, Fredericks Z, Kranz J, et al.
Chem Biol
. 2000 Feb;
7(1):17-25.
PMID: 10662687
Background: The rapidly expanding list of pharmacologically important targets has highlighted the need for ways to discover new inhibitors that are independent of functional assays. We have utilized peptides to...
7.
Wijayaratne A, Nagel S, Paige L, Christensen D, Norris J, Fowlkes D, et al.
Endocrinology
. 1999 Dec;
140(12):5828-40.
PMID: 10579349
Antiestrogens such as tamoxifen are one of the most effective methods of treating estrogen receptor (ERalpha) positive breast cancers; however, the effectiveness of this therapy is limited by the almost...
8.
Norris J, Paige L, Christensen D, Chang C, Huacani M, Fan D, et al.
Science
. 1999 Jul;
285(5428):744-6.
PMID: 10426998
Estrogen receptor alpha transcriptional activity is regulated by distinct conformational states that are the result of ligand binding. Phage display was used to identify peptides that interact specifically with either...
9.
Paige L, Christensen D, Gron H, Norris J, Gottlin E, Padilla K, et al.
Proc Natl Acad Sci U S A
. 1999 Mar;
96(7):3999-4004.
PMID: 10097152
Estrogen receptor (ER) modulators produce distinct tissue-specific biological effects, but within the confines of the established models of ER action it is difficult to understand why. Previous studies have suggested...
10.
Christensen D, Poulter C
Bioorg Med Chem
. 1994 Jul;
2(7):631-7.
PMID: 7858969
Recombinant yeast isopentenyl diphosphate (IPP) isomerase and avian farnesyl diphosphate (FPP) synthase from overproducing strains of Escherichia coli were used to synthesize FPP from IPP and dimethylallyl diphosphate (DMAPP). [2,4,5-13C3]IPP...