D P McDonnell
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Explore the profile of D P McDonnell including associated specialties, affiliations and a list of published articles.
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100
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3959
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Recent Articles
1.
Tang X, Ding C, Wu J, Sjol J, Wardell S, Spasojevic I, et al.
Oncogene
. 2017 Jun;
36(30):4379.
PMID: 28604749
This corrects the article DOI: 10.1038/onc.2016.394.
2.
Tang X, Ding C, Wu J, Sjol J, Wardell S, Spasojevic I, et al.
Oncogene
. 2016 Nov;
36(30):4235-4242.
PMID: 27869167
Despite the advances in the diagnosis and treatment of breast cancer, breast cancers still cause significant mortality. For some patients, especially those with triple-negative breast cancer, current treatments continue to...
3.
McDonnell D, Chang C, Nelson E
Climacteric
. 2014 Oct;
17 Suppl 2:60-5.
PMID: 25320023
Despite increased survivorship among patients, breast cancer remains the most common cancer among women and is the second leading cause of cancer death in women. The magnitude of this problem...
4.
Shatnawi A, Norris J, Chaveroux C, Jasper J, Sherk A, McDonnell D, et al.
Oncogene
. 2013 Feb;
33(7):862-71.
PMID: 23435425
The androgen receptor (AR) has a critical role in the development and progression of prostate cancer (PC) and is a major therapeutic target in this disease. The transcriptional activity of...
5.
Ascher-Svanum H, Peng X, Montgomery W, Faries D, Lawson A, Witte M, et al.
Eur Psychiatry
. 2010 Jul;
26(5):313-9.
PMID: 20621454
Objective: Adding another antipsychotic to a treatment regimen was previously used in evaluating the medication's efficacy. Supplementation of depot antipsychotics with oral antipsychotics is particularly meaningful because depot formulations are...
6.
Stein R, McDonnell D
Endocr Relat Cancer
. 2007 Jan;
13 Suppl 1:S25-32.
PMID: 17259555
The orphan receptor estrogen-related receptor alpha (ERR alpha) is a member of the nuclear receptor superfamily of ligand-regulated transcription factors. This protein is structurally most related to the canonical estrogen...
7.
Weatherman R, Chang C, Clegg N, Carroll D, Day R, Baxter J, et al.
Mol Endocrinol
. 2002 Mar;
16(3):487-96.
PMID: 11875107
Some aspects of ligand-regulated transcription activation by the estrogen receptor (ER) are associated with the estrogen-dependent formation of a hydrophobic cleft on the receptor surface. At least in vitro, this...
8.
Capitalizing on the complexities of estrogen receptor pharmacology in the quest for the perfect SERM
McDonnell D, Chang C, Norris J
Ann N Y Acad Sci
. 2002 Jan;
949:16-35.
PMID: 11795348
The term Selective Estrogen Receptor Modulators (SERMs) has been used of late to describe a group of pharmaceuticals that manifest estrogen receptor (ER) agonist activity in some tissues, but that...
9.
Chang C, Walther P, McDonnell D
Cancer Res
. 2001 Dec;
61(24):8712-7.
PMID: 11751389
The pathophysiological mechanism(s) by which androgen independence develops in prostate cancer remains to be determined. The identification in many prostate cancer specimens of a mutant androgen receptor, T877A, with altered...
10.
Nagel S, Hagelbarger J, McDonnell D
Endocrinology
. 2001 Oct;
142(11):4721-8.
PMID: 11606437
We have developed a transgenic mouse that functions as a reporter of ER activity, termed ER action indicator (ERIN), by incorporating a transgene with an estrogen-responsive promoter (three copies of...