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D G Beer

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Articles 65
Citations 974
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Recent Articles
1.
Xi S, Inchauste S, Guo H, Shan J, Xiao Z, Xu H, et al.
Oncogene . 2015 Feb; 34(44):5548-59. PMID: 25703328
Although microRNAs (miRs) have been implicated in the pathogenesis of various human malignancies, limited information is available regarding mechanisms by which these noncoding RNAs contribute to initiation and progression of...
2.
Pal J, Bertheau R, Buon L, Qazi A, Batchu R, Bandyopadhyay S, et al.
Oncogene . 2011 Mar; 30(33):3585-98. PMID: 21423218
A prominent feature of most cancers including Barrett's adenocarcinoma (BAC) is genetic instability, which is associated with development and progression of disease. In this study, we investigated the role of...
3.
Miller C, Lin L, Casper A, Lim J, Thomas D, Orringer M, et al.
Oncogene . 2005 Sep; 25(3):409-18. PMID: 16186806
Esophageal adenocarcinoma (EA) is characterized by a poor prognosis making the identification of clinically targetable proteins essential for improving patient outcome. We report the involvement of multiple alterations of the...
4.
Daly E, Chen G, Sun L, Friedlander M, Goldstein D, Beer D, et al.
Int J Biol Markers . 2004 Jul; 19(2):170-2. PMID: 15255553
No abstract available.
5.
Giordano T, Shedden K, Schwartz D, Kuick R, Taylor J, Lee N, et al.
Am J Pathol . 2001 Oct; 159(4):1231-8. PMID: 11583950
Molecular classification of tumors based on their gene expression profiles promises to significantly refine diagnosis and management of cancer patients. The establishment of organ-specific gene expression patterns represents a crucial...
6.
Brichory F, Misek D, Yim A, Krause M, Giordano T, Beer D, et al.
Proc Natl Acad Sci U S A . 2001 Aug; 98(17):9824-9. PMID: 11504947
The identification of circulating tumor antigens or their related autoantibodies provides a means for early cancer diagnosis as well as leads for therapy. The purpose of this study was to...
7.
Fang J, Arlt M, Burgess A, Dagenais S, Beer D, Glover T
Genes Chromosomes Cancer . 2001 Feb; 30(3):292-8. PMID: 11170287
Common fragile sites have been proposed to play a mechanistic role in chromosome translocations and other rearrangements in cancer cells in vivo based on their behavior in vitro and their...
8.
Lin L, Prescott M, Zhu Z, Singh P, Chun S, Kuick R, et al.
Cancer Res . 2001 Jan; 60(24):7021-7. PMID: 11156406
Genomic DNA amplification in tumors is frequently associated with an increased gene copy number of oncogenes or other cancer-related genes. We have used a two-dimensional whole-genome scanning technique to identify...
9.
Kawakami K, Brabender J, Lord R, Groshen S, Greenwald B, Krasna M, et al.
J Natl Cancer Inst . 2000 Nov; 92(22):1805-11. PMID: 11078757
Background: The adenomatous polyposis coli (APC) locus on chromosome 5q21-22 shows frequent loss of heterozygosity (LOH) in esophageal carcinomas. However, the prevalence of truncating mutations in the APC gene in...
10.
Souza R, Shewmake K, Beer D, Cryer B, Spechler S
Cancer Res . 2000 Nov; 60(20):5767-72. PMID: 11059772
Adenocarcinoma in Barrett's esophagus has been increasing in incidence at a rapid rate for more than two decades. Cyclooxygenase (COX)-2 appears to play an important role in gastrointestinal carcinogenesis, and...