D E Malarkey
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Explore the profile of D E Malarkey including associated specialties, affiliations and a list of published articles.
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Articles
31
Citations
471
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Recent Articles
1.
Hart-Unger S, Arao Y, Hamilton K, Lierz S, Malarkey D, Hewitt S, et al.
Int J Obes (Lond)
. 2017 Feb;
41(6):945-954.
PMID: 28220039
Background: Treatment with estrogen in early menopausal women protects against development of hepatic steatosis and nonalcoholic fatty liver disease but estrogen has undesirable side effects, which negate its beneficial effects...
2.
Milovancev M, Hauck M, Keller C, Stranahan L, Mansoor A, Malarkey D
J Comp Pathol
. 2014 Dec;
152(1):22-7.
PMID: 25435513
Comparative analyses of canine and human soft tissue sarcomas (STSs) are lacking. This study compared the histological and immunohistochemical (labelling for desmin, smooth muscle actin [SMA], CD31, pancytokeratin, S100 and...
3.
Chernoff N, Rogers E, Zehr R, Gage M, Travlos G, Malarkey D, et al.
J Toxicol Environ Health A
. 2014 Jul;
77(17):1040-60.
PMID: 25072824
Cylindrospermopsin (CYN) is a toxin produced by a variety of fresh-water cyanobacterial species worldwide and induces significant adverse effects in both livestock and humans. This study investigated the course of...
4.
Kane A, DeFrancesco T, Boyle M, Malarkey D, Ritchey J, Atkins C, et al.
Res Vet Sci
. 2012 Dec;
94(3):610-7.
PMID: 23231955
This investigation tested the hypothesis that carriers of golden retriever muscular dystrophy (GRMD), a genetically homologous condition of Duchenne muscular dystrophy (DMD), have quantifiable abnormalities in myocardial function, structure, or...
5.
HALL A, Elcombe C, Foster J, Harada T, Kaufmann W, Knippel A, et al.
Toxicol Pathol
. 2012 Jun;
40(7):971-94.
PMID: 22723046
Preclinical toxicity studies have demonstrated that exposure of laboratory animals to liver enzyme inducers during preclinical safety assessment results in a signature of toxicological changes characterized by an increase in...
6.
Chernoff N, Rogers E, Zehr R, Gage M, Malarkey D, Bradfield C, et al.
J Appl Toxicol
. 2010 Oct;
31(3):242-54.
PMID: 20936652
Cylindrospermopsin (CYN) is a tricyclic alkaloid toxin produced by fresh water cyanobacterial species worldwide. CYN has been responsible for both livestock and human poisoning after oral exposure. This study investigated...
7.
Singh B, Nyska A, Kissling G, Lieuallen W, Johansson S, Malarkey D, et al.
Toxicol Pathol
. 2010 Mar;
38(3):372-81.
PMID: 20233943
B6C3F1 mice chronically exposed to 3,3',4,4'-tetrachloroazobenzene (TCAB), a contaminant of dichloroaniline-derived herbicides, developed a number of neoplastic and nonneoplastic lesions, including carcinoma of the urinary tract. Groups of fifty male...
8.
Looper J, Malarkey D, Ruslander D, Proulx D, Thrall D
Vet Comp Oncol
. 2009 Sep;
4(1):33-40.
PMID: 19754827
Feline oral squamous cell carcinomas (SCC) have a poor prognosis despite aggressive treatment with surgery, radiation and anticancer drugs. Overexpression of the epidermal growth factor receptor (EGFR), a membrane-bound tyrosine...
9.
Shiomitsu K, Johnson C, Malarkey D, Pruitt A, Thrall D
Vet Comp Oncol
. 2009 May;
7(2):106-14.
PMID: 19453364
Epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) signalling pathways play a role in carcinogenesis. Inhibition of EGF receptor (EGFR) and of VEGF is effective in increasing the...
10.
Stout M, Nyska A, Collins B, Witt K, Kissling G, Malarkey D, et al.
Food Chem Toxicol
. 2009 Jan;
47(4):729-33.
PMID: 19166900
Trivalent chromium (Cr(III)) has been proposed to be an essential element, which may increase sensitivity to insulin and thus participate in carbohydrate and lipid metabolism. Humans ingest Cr(III) both as...