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D E Heinrichs

Explore the profile of D E Heinrichs including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 15
Citations 981
Followers 0
Related Specialties
Microbiology
Biochemistry
Allergy & Immunology
Top 10 Co-Authors
K Poole
C Whitfield
J A Yethon
S Neshat
M A Monteiro
M T Sebulsky
M B Perry
K Ziebell
K Amor
Q Zhao
Published In
J Bacteriol
J Biol Chem
Infect Immun
Mol Microbiol
Antimicrob Agents Chemother
Affiliations
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Recent Articles
1.
Attenuation of massive cytokine response to the staphylococcal enterotoxin B superantigen by the innate immunomodulatory protein lactoferrin
Hayworth J, Kasper K, Leon-Ponte M, Herfst C, Yue D, Brintnell W, et al.
Clin Exp Immunol . 2009 Aug; 157(1):60-70. PMID: 19659771
Staphylococcal enterotoxin B (SEB) is a pyrogenic exotoxin and a potent superantigen which causes massive T cell activation and cytokine secretion, leading to profound immunosuppression and morbidity. The inhibition of...
2.
Identification and characterization of fhuD1 and fhuD2, two genes involved in iron-hydroxamate uptake in Staphylococcus aureus
Sebulsky M, Heinrichs D
J Bacteriol . 2001 Aug; 183(17):4994-5000. PMID: 11489851
Staphylococcus aureus can utilize several hydroxamate siderophores for growth under iron-restricted conditions. Previous findings have shown that S. aureus possesses a cytoplasmic membrane-associated traffic ATPase that is involved in the...
3.
Identification and characterization of a membrane permease involved in iron-hydroxamate transport in Staphylococcus aureus
Sebulsky M, Hohnstein D, Hunter M, Heinrichs D
J Bacteriol . 2000 Jul; 182(16):4394-400. PMID: 10913070
Staphylococcus aureus was shown to transport iron complexed to a variety of hydroxamate type siderophores, including ferrichrome, aerobactin, and desferrioxamine. An S. aureus mutant defective in the ability to transport...
4.
Distribution of core oligosaccharide types in lipopolysaccharides from Escherichia coli
Amor K, Heinrichs D, Frirdich E, Ziebell K, Johnson R, Whitfield C
Infect Immun . 2000 Feb; 68(3):1116-24. PMID: 10678915
In the lipopolysaccharides of Escherichia coli there are five distinct core oligosaccharide (core OS) structures, designated K-12 and R1 to R4. The objective of this work was to determine the...
5.
Characterization of dTDP-4-dehydrorhamnose 3,5-epimerase and dTDP-4-dehydrorhamnose reductase, required for dTDP-L-rhamnose biosynthesis in Salmonella enterica serovar Typhimurium LT2
Graninger M, Nidetzky B, Heinrichs D, Whitfield C, Messner P
J Biol Chem . 1999 Aug; 274(35):25069-77. PMID: 10455186
The thymidine diphosphate-L-rhamnose biosynthesis pathway is required for assembly of surface glycoconjugates in a growing list of bacterial pathogens, making this pathway a potential therapeutic target. However, the terminal reactions...
6.
The assembly system for the outer core portion of R1- and R4-type lipopolysaccharides of Escherichia coli. The R1 core-specific beta-glucosyltransferase provides a novel attachment site for O-polysaccharides
Heinrichs D, Yethon J, Amor P, Whitfield C
J Biol Chem . 1998 Oct; 273(45):29497-505. PMID: 9792656
The major core oligosaccharide biosynthesis operons from prototype Escherichia coli strains displaying R1 and R4 lipopolysaccharide core types were polymerase chain reaction-amplified and analyzed. Comparison of deduced products of the...
7.
Molecular basis for structural diversity in the core regions of the lipopolysaccharides of Escherichia coli and Salmonella enterica
Heinrichs D, Yethon J, Whitfield C
Mol Microbiol . 1998 Oct; 30(2):221-32. PMID: 9791168
Bacterial lipopolysaccharides (LPS) are unique and complex glycolipids that provide characteristic components of the outer membranes of Gram-negative bacteria. In LPS of the Enterobacteriaceae, the core oligosaccharide links a highly...
8.
Involvement of waaY, waaQ, and waaP in the modification of Escherichia coli lipopolysaccharide and their role in the formation of a stable outer membrane
Yethon J, Heinrichs D, Monteiro M, Perry M, Whitfield C
J Biol Chem . 1998 Oct; 273(41):26310-6. PMID: 9756860
The waaY, waaQ, and waaP genes are located in the central operon of the waa (formerly rfa) locus on the chromosome of Escherichia coli. This locus contains genes whose products...
9.
The assembly system for the lipopolysaccharide R2 core-type of Escherichia coli is a hybrid of those found in Escherichia coli K-12 and Salmonella enterica. Structure and function of the R2 WaaK and WaaL homologs
Heinrichs D, Monteiro M, Perry M, Whitfield C
J Biol Chem . 1998 May; 273(15):8849-59. PMID: 9535865
In Escherichia coli F632, the 14-kilobase pair chromosomal region located between waaC (formerly rfaC) and waaA (kdtA) contains genes encoding enzymes required for the synthesis of the type R2 core...
10.
Expression of the multidrug resistance operon mexA-mexB-oprM in Pseudomonas aeruginosa: mexR encodes a regulator of operon expression
Poole K, Tetro K, Zhao Q, Neshat S, Heinrichs D, Bianco N
Antimicrob Agents Chemother . 1996 Sep; 40(9):2021-8. PMID: 8878574
The region upstream of the multiple antibiotic resistance efflux operon mexA-mexB-oprM in Pseudomonas aeruginosa was sequenced, and a gene, mexR, was identified. The predicted MexR product contains 147 amino acids...