D D Loo
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Explore the profile of D D Loo including associated specialties, affiliations and a list of published articles.
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66
Citations
1961
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Recent Articles
1.
Meinild A, Loo D, Hirayama B, Gallardo E, Wright E
Biochemistry
. 2001 Sep;
40(39):11897-904.
PMID: 11570890
We mutated residue 166, located in the putative Na(+) transport pathway between transmembrane segments 4 and 5 of human Na(+)/glucose cotransporter (hSGLT1), from alanine to cysteine (A166C). A166C was expressed...
2.
Zeuthen T, Meinild A, Loo D, Wright E, Klaerke D
J Physiol
. 2001 Mar;
531(Pt 3):631-44.
PMID: 11251046
1. In order to study its role in steady state water transport, the Na+-glucose cotransporter (SGLT1) was expressed in Xenopus laevis oocytes; both the human and the rabbit clones were...
3.
Wright E, Loo D
Ann N Y Acad Sci
. 2001 Feb;
915:54-66.
PMID: 11193601
Water is absorbed across the small intestine in the absence of external driving forces. However, it has been established that water transport is secondary to active sodium transport. In the...
4.
Leung D, Loo D, Hirayama B, Zeuthen T, Wright E
J Physiol
. 2000 Oct;
528 Pt 2:251-7.
PMID: 11034615
The rabbit Na+-glucose cotransporter (rbSGLT1) was expressed in Xenopus laevis oocytes and urea transport in rbSGLT1 and non-injected (control) oocytes was studied using [14C]urea as a tracer. The level of...
5.
Quick M, Loo D, Wright E
J Biol Chem
. 2000 Oct;
276(3):1728-34.
PMID: 11024018
The role of conserved Asp204 in the human high affinity Na+/glucose cotransporter (hSGLT1) was investigated by site-directed mutagenesis combined with functional assays exploiting the Xenopus oocyte expression system. Substitution of...
6.
Loo D, Eskandari S, Boorer K, Sarkar H, Wright E
J Biol Chem
. 2000 Sep;
275(48):37414-22.
PMID: 10973981
We have investigated the functional role of Cl(-) in the human Na(+)/Cl(-)/gamma-aminobutyric acid (GABA) and Na(+)/glucose cotransporters (GAT1 and SGLT1, respectively) expressed in Xenopus laevis oocytes. Substrate-evoked steady-state inward currents...
7.
Dresser M, Gerstin K, Gray A, Loo D, Giacomini K
Drug Metab Dispos
. 2000 Aug;
28(9):1135-40.
PMID: 10950861
Nucleoside transporters that mediate cellular uptake of therapeutic nucleoside analogs are major determinants of the pharmacokinetic properties of these compounds. Understanding the substrate selectivity of these transporters is critical in...
8.
Meinild A, Loo D, Pajor A, Zeuthen T, Wright E
Am J Physiol Renal Physiol
. 2000 May;
278(5):F777-83.
PMID: 10807589
This study investigated the ability of the renal Na(+)-dicarboxylate cotransporter, NaDC-1, to transport water. Rabbit NaDC-1 was expressed in Xenopus laevis oocytes, cotransporter activity was measured as the inward current...
9.
Loo D, Hirayama B, Meinild A, Chandy G, Zeuthen T, Wright E
J Physiol
. 1999 Jun;
518(Pt 1):195-202.
PMID: 10373701
1. The rabbit Na+-glucose (SGLT1) and the human Na+-Cl--GABA (GAT1) cotransporters were expressed in Xenopus laevis oocytes, and passive Na+ and water transport were studied using electrical and optical techniques....
10.
Forster I, Loo D, Eskandari S
Am J Physiol
. 1999 Apr;
276(4):F644-9.
PMID: 10198426
The stoichiometry of the rat and flounder isoforms of the renal type II sodium-phosphate (Na+-Pi) cotransporter was determined directly by simultaneous measurements of phosphate (Pi)-induced inward current and uptake of...