D A Young
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Explore the profile of D A Young including associated specialties, affiliations and a list of published articles.
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273
Citations
3807
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Recent Articles
1.
Chaudhry N, Muhammad H, Seidl C, Downes D, Young D, Hao Y, et al.
Osteoarthritis Cartilage
. 2022 Jan;
30(4):596-604.
PMID: 35074547
Objective: MicroRNA 140 (miR-140) is a chondrocyte-specific endogenous gene regulator implicated in osteoarthritis (OA). As mechanical injury is a primary aetiological factor in OA, we investigated miR-140-dependent mechanosensitive gene regulation...
2.
Young D, Barter M, Soul J
Osteoarthritis Cartilage
. 2021 Nov;
30(2):216-225.
PMID: 34774787
Objective: In this review, we have highlighted the advances over the past year in genetics, genomics and epigenetics in the field of osteoarthritis (OA). Methods: A literature search of PubMed...
3.
Patel K, Chandrasegaran S, Clark I, Proctor C, Young D, Shanley D
Bioinformatics
. 2021 May;
37(20):3604-3609.
PMID: 33993215
Motivation: The analysis of longitudinal datasets and construction of gene regulatory networks (GRNs) provide a valuable means to disentangle the complexity of microRNA (miRNA)-mRNA interactions. However, there are no computational...
4.
Ajekigbe B, Cheung K, Xu Y, Skelton A, Panagiotopoulos A, Soul J, et al.
Osteoarthritis Cartilage
. 2019 Jan;
27(4):694-702.
PMID: 30611906
Objective: Long intergenic non-coding RNAs (lincRNAs) are emerging as key regulators in gene expression; however, little is known about the lincRNA expression changes that occur in osteoarthritis (OA). Here we...
5.
Urquhart O, Tampi M, Pilcher L, Slayton R, Araujo M, Fontana M, et al.
J Dent Res
. 2018 Oct;
98(1):14-26.
PMID: 30290130
The goal of nonrestorative or non- and microinvasive caries treatment (fluoride- and nonfluoride-based interventions) is to manage the caries disease process at a lesion level and minimize the loss of...
6.
Mei-Dan O, Jewell D, Garabekyan T, Brockwell J, Young D, McBryde C, et al.
Bone Joint J
. 2017 Jun;
99-B(6):724-731.
PMID: 28566390
Aims: The aim of this study was to evaluate the long-term clinical and radiographic outcomes of the Birmingham Interlocking Pelvic Osteotomy (BIPO). Patients And Methods: In this prospective study, we...
7.
Furth D, Young D
Oecologia
. 2017 Mar;
74(4):496-500.
PMID: 28311754
Eighteen leaf flavonoid compounds were isolated from several populations of Rhus tripartita from xeric habitats in Israel, ornamental Schinus terebinthifolius from Israel, and three species of Rhus (vulgaris, natalensis, tenuinervis)...
8.
Pierrepont J, Feyen H, Miles B, Young D, Bare J, Shimmin A
Bone Joint J
. 2016 Jul;
98-B(7):910-6.
PMID: 27365468
Aims: Long-term clinical outcomes for ceramic-on-ceramic (CoC) bearings are encouraging. However, there is a risk of squeaking. Guidelines for the orientation of the acetabular component are defined from static imaging,...
9.
Aitken A, Roberts J, van Ommen T, Young D, Golledge N, Greenbaum J, et al.
Nature
. 2016 May;
533(7603):385-9.
PMID: 27193684
Climate variations cause ice sheets to retreat and advance, raising or lowering sea level by metres to decametres. The basic relationship is unambiguous, but the timing, magnitude and sources of...
10.
Young D, Schroeder D, Blankenship D, Kempf S, Quartini E
Philos Trans A Math Phys Eng Sci
. 2015 Dec;
374(2059).
PMID: 26667910
Antarctica's subglacial lakes have two end member geophysical expressions: as hydraulically flat, radar reflective regions highlighted in ice surface topography and radar sounding profiles ('definite lakes'), and as localized sites...