D A Wink
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Explore the profile of D A Wink including associated specialties, affiliations and a list of published articles.
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103
Citations
4391
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Recent Articles
1.
Kovacevic Z, Sahni S, Lok H, Davies M, Wink D, Richardson D
Biochim Biophys Acta Gen Subj
. 2017 Feb;
1861(5 Pt A):995-999.
PMID: 28219722
We recently demonstrated that a novel storage and transport mechanism for nitric oxide (NO) mediated by glutathione-S-transferase P1 (GSTP1) and multidrug resistance protein 1 (MRP1/ABCC1), protects M1-macrophage (M1-MØ) models from...
2.
Wink D, Kim S, Miles A, Jourdheuil D, Grisham M
Curr Protoc Toxicol
. 2012 Oct;
Chapter 10:Unit 10.4.
PMID: 23045026
Recently fluorometric techniques have been developed to determine NO and S-nitrosothiols with improved sensitivity over spectrophotometric techniques based on similar chemistry. This unit contains protocols for detection and quantification of...
3.
Switzer C, Cheng R, Vitek T, Christensen D, Wink D, Vitek M
Oncogene
. 2011 Feb;
30(22):2504-13.
PMID: 21297667
The SET oncoprotein participates in cancer progression by affecting multiple cellular processes, inhibiting the tumor suppressor protein phosphatase 2A (PP2A), and inhibiting the metastasis suppressor nm23-H1. On the basis of...
4.
Wink D, Kim S, Miles A, Jourdheuil D, Grisham M
Curr Protoc Toxicol
. 2010 Oct;
Chapter 10:Unit 10.8.
PMID: 20957636
NO-derived intermediates formed under aerobic conditions may engage in complex chemical reactions with biologically important molecules. The outcomes of these reactions and their ultimate effect on biological systems depend on...
5.
Switzer C, Ridnour L, Cheng R, Sparatore A, Del Soldato P, Moody T, et al.
Oncogene
. 2009 Aug;
28(43):3837-46.
PMID: 19701246
The chemopreventative effects of dithiolethione compounds are attributed to their activation of antioxidant response elements (AREs) by reacting with the Nrf2/Keap1 protein complex. In this study, we show antiproliferative effects...
6.
Isenberg J, Jia Y, Field L, Ridnour L, Sparatore A, Del Soldato P, et al.
Br J Pharmacol
. 2007 Mar;
151(1):63-72.
PMID: 17351657
Background And Purpose: Angiogenesis involves multiple signaling pathways that must be considered when developing agents to modulate pathological angiogenesis. Because both cyclooxygenase inhibitors and dithioles have demonstrated anti-angiogenic properties, we...
7.
Colton C, Vitek M, Wink D, Xu Q, Cantillana V, Previti M, et al.
Proc Natl Acad Sci U S A
. 2006 Aug;
103(34):12867-72.
PMID: 16908860
Alzheimer's disease is characterized by two primary pathological features: amyloid plaques and neurofibrillary tangles. The interconnection between amyloid and tau aggregates is of intense interest, but mouse models have yet...
8.
Colton C, Gbadegesin M, Wink D, Miranda K, Espey M, Vicini S
J Neurochem
. 2001 Sep;
78(5):1126-34.
PMID: 11553686
Nitric oxide (NO) is an important regulator of NMDA channel function in the CNS. Recent findings suggest that nitroxyl anion (NO(-)) may also be generated by nitric oxide synthase, which...
9.
Paolocci N, Saavedra W, Miranda K, Martignani C, Isoda T, Hare J, et al.
Proc Natl Acad Sci U S A
. 2001 Aug;
98(18):10463-8.
PMID: 11517312
Nitroxyl anion (NO(-)) is the one-electron reduction product of nitric oxide (NO( small middle dot)) and is enzymatically generated by NO synthase in vitro. The physiologic activity and mechanism of...
10.
Wink D, Miranda K, Espey M
Exp Biol Med (Maywood)
. 2001 Jul;
226(7):621-3.
PMID: 11444095
No abstract available.