D A Durden
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Explore the profile of D A Durden including associated specialties, affiliations and a list of published articles.
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62
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269
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Recent Articles
1.
Durden D, Dyck L, Davis B, Liu Y, Boulton A
Drug Metab Dispos
. 2000 Jan;
28(2):147-54.
PMID: 10640511
(R)-N-(2-Heptyl)-N-methylpropargylamine (R-2HMP) is a monoamine oxidase inhibitor and putative antiapoptotic agent analogous to (R)-deprenyl. In the rat, the major amine metabolites of R-2HMP have been identified as (R)-N-2-heptylmethylamine (R-2HMA), (R)-N-2-heptylpropargylamine...
2.
Boulton A, Yu P, Davis B, Paterson I, Li X, Juorio A, et al.
Adv Pharmacol
. 1997 Nov;
42:308-11.
PMID: 9327902
No abstract available.
3.
Durden D, Davis B, Boulton A
J Chromatogr B Biomed Sci Appl
. 1997 Feb;
689(1):165-73.
PMID: 9061491
The chromatographic properties of (R)-(+)-N-(trifluoroacetyl)prolyl and (S)-(-)-N-(trifluoroacetyl)prolyl derivatives on a chiral gas chromatography capillary column were assessed for the measurement of enantiomeric purities of 2-butylamine, 2-pentylamine, 2-hexylamine, 2-heptylamine and 2-octylamine...
4.
Paterson I, Davis B, Durden D, Juorio A, Yu P, Ivy G, et al.
Neurochem Res
. 1995 Dec;
20(12):1503-10.
PMID: 8789614
The present study has examined whether MAO-B has a role in DA metabolism in the primate CNS in situ. Eleven macaques (macaca facicularis) were used in this study to examine...
5.
Milgram N, Ivy G, Murphy M, Head E, Wu P, Ruehl W, et al.
Pharmacol Biochem Behav
. 1995 Jun;
51(2-3):421-8.
PMID: 7667363
Dogs were administered capsules containing L-deprenyl daily over 3 weeks at dose levels of 0, 0.1, 0.5, and 1.0 mg/kg. Spontaneous behavior was measured using a canine open field test,...
6.
Davis B, Kennedy S, DSouza J, Durden D, Goldbloom D, Boulton A
J Psychiatry Neurosci
. 1994 Jul;
19(4):282-8.
PMID: 7918350
Women with bulimia nervosa undergoing treatment with the reversible monoamine oxidase type A inhibitor, brofaromine, were rated for mood and eating behaviour and their plasma and urine were assessed for...
7.
Yu P, Davis B, Durden D, Barber A, Terleckyj I, Nicklas W, et al.
J Neurochem
. 1994 Feb;
62(2):697-704.
PMID: 8294932
Aliphatic N-propargylamines have recently been discovered to be highly potent, selective, and irreversible monoamine oxidase B (MAO-B) inhibitors. N-Methyl-N-(2-pentyl)propargylamine (M-2-PP) and N-methyl-N-(2-hexyl) propargylamine (2-HxMP), for example, are approximately fivefold more...
8.
Milgram N, Ivy G, Head E, Murphy M, Wu P, Ruehl W, et al.
Neurochem Res
. 1993 Dec;
18(12):1211-9.
PMID: 8272186
Behavioral and pharmacological effects of oral administration of L-deprenyl in the dog are described. Spontaneous behavior is unaffected at doses below 3 mg/kg while at higher doses there was stereotypical...
9.
Durden D, Davis B
Neurochem Res
. 1993 Sep;
18(9):995-1002.
PMID: 8232728
Using a new ultrasensitive method the trace biogenic amines, phenylethylamine, meta-tyramine and para-tyramine have been quantitated in brain regions obtained from a single rat. Phenylethylamine concentrations in ng/g wet tissue...
10.
Davis B, Kennedy S, Durden D, DSouza J, Goldbloom D, Boulton A
Prog Neuropsychopharmacol Biol Psychiatry
. 1993 Sep;
17(5):747-63.
PMID: 7504824
1. Brofaromine or placebo were administered to female bulimia nervosa patients over a period of eight weeks. Plasma and urinary trace amines, their acidic metabolites and the acidic metabolites of...