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Csilla Ozvegy-Laczka

Explore the profile of Csilla Ozvegy-Laczka including associated specialties, affiliations and a list of published articles. Areas
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Articles 67
Citations 1385
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Recent Articles
1.
Bakos E, Agoston H, Ignacz R, Hunyadi A, Poor M, Erostyak J, et al.
Int J Mol Sci . 2025 Feb; 26(4). PMID: 40003948
Rosamines represent one of the most promising groups of xanthene dyes. Their excellent photophysical properties allow their widespread application. Their use as photosensitizers in photodynamic therapy has recently gained considerable...
2.
Bakos E, Bujdoso-Szekely V, Patik I, Kiraly L, Lango T, Kozak E, et al.
Eur J Pharm Sci . 2025 Feb; :107046. PMID: 39983930
Cancer-type Organic anion transporting polypeptide 1B3, ct-OATP1B3-V1 is a tumor-specific isoform of liver-type OATP1B3 (Lt-OATP1B3). Ct-OATP1B3-V1 is identical with liver-specific Lt-OATP1B3 except it lacks the first 28 amino acids. Although...
3.
Stefan K, Puri S, Rafehi M, Latambale G, Neif M, Tagl F, et al.
Eur J Med Chem . 2025 Feb; 287:117234. PMID: 39892094
Despite the significant roles of solute carrier (SLC) and ATP-binding cassette (ABC) transporters in human health and disease, most remain poorly characterized as intrinsic and/or xenobiotic ligands are unknown, rendering...
4.
Dombi A, Kaci H, Valentova K, Bakos E, Ozvegy-Laczka C, Poor M
Pharmacol Res Perspect . 2024 Sep; 12(5):e70021. PMID: 39344282
Myricetin (MYR) and ampelopsin (AMP, or dihydromyricetin) are flavonoid aglycones found in certain plants and dietary supplements. During the presystemic biotransformation of flavonoids, mainly sulfate and glucuronide derivatives are produced,...
5.
Perina M, Borzsei R, Agoston H, Hlogyik T, Poor M, Rigo R, et al.
Eur J Pharm Sci . 2024 May; 199:106813. PMID: 38797442
Novel BODIPY-estradiol conjugates have been synthesized by selecting position C-3-O for labeling. The conjugation strategy was based on Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) or etherification. Estradiol derivatives used as azide partners...
6.
Kaci H, Bakos E, Needs P, Kroon P, Valentova K, Poor M, et al.
Eur J Pharm Sci . 2024 Mar; 196:106740. PMID: 38437885
Organic anion transporting polypeptides (OATPs), OATP1B1 and OATP2B1 are membrane proteins mediating the cellular uptake of chemically diverse organic compounds. OATP1B1 is exclusively expressed in hepatocytes and plays a key...
7.
Kaci H, Dombi A, Gombos P, Szabo A, Bakos E, Ozvegy-Laczka C, et al.
Toxicol In Vitro . 2024 Feb; 96:105789. PMID: 38341109
Zearalenone (ZEN) is a mycoestrogen produced by Fusarium fungi. ZEN is a frequent contaminant in cereal-based products, representing significant health threat. The major reduced metabolites of ZEN are α-zearalenol (α-ZEL)...
8.
Ungvari O, Bakos E, Kovacsics D, Ozvegy-Laczka C
FASEB J . 2023 Oct; 37(11):e23223. PMID: 37781971
Organic anion transporting polypeptides OATP1A2, OATP1B1, OATP1B3 and OATP2B1 are Na - and ATP-independent exchangers of large, organic compounds, encompassing structurally diverse xenobiotics, including various drugs. These OATPs influence intestinal...
9.
Bakos E, Temesszentandrasi-Ambrus C, Ozvegy-Laczka C, Gaborik Z, Sarkadi B, Telbisz A
Int J Mol Sci . 2023 Jul; 24(14). PMID: 37510996
Orally administered small molecules may have important therapeutic potential in treating COVID-19 disease. The recently developed antiviral agents, Molnupiravir and Nirmatrelvir, have been reported to be efficient treatments, with only...
10.
Hlogyik T, Laczko-Rigo R, Bakos E, Poor M, Kele Z, Ozvegy-Laczka C, et al.
Org Biomol Chem . 2023 Jul; 21(29):6018-6027. PMID: 37436113
Aza-BODIPY dyes have recently come to attention owing to their excellent chemical and photophysical properties. In particular, their absorption and emission maxima can efficiently be shifted to the red or...