Cristina Segnani
Overview
Explore the profile of Cristina Segnani including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
574
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Recent Articles
1.
DAntongiovanni V, Fornai M, Colucci R, Nericcio A, Benvenuti L, Di Salvo C, et al.
Acta Physiol (Oxf)
. 2024 Sep;
241(1):e14232.
PMID: 39287080
Aim: In the present study, we investigated the involvement of NLRP3 inflammasome in the intestinal epithelial barrier (IEB) changes associated with obesity, and its role in the interplay between enteric...
2.
Bellini G, Rettura F, Palermo G, Ippolito C, Segnani C, Pierucci C, et al.
Mov Disord
. 2024 Jul;
39(11):2091-2097.
PMID: 39051733
Background: Elevated levels of prokineticin-2 (PK2), regarded as a protein involved in modulating immune/inflammatory responses, have been detected in the substantia nigra, serum, and olfactory neurons of Parkinson's disease (PD)...
3.
DAntongiovanni V, Segnani C, Ippolito C, Antonioli L, Colucci R, Fornai M, et al.
Lab Invest
. 2023 Jun;
103(10):100194.
PMID: 37290605
Intestinal barrier alterations represent a primum movens in obesity and related intestinal dysfunctions. However, whether gut barrier remodeling represents prodromal events in obesity before weight gain, metabolic alterations, and systemic...
4.
Benvenuti L, DAntongiovanni V, Pellegrini C, Fornai M, Bernardini N, Ippolito C, et al.
Mol Nutr Food Res
. 2023 Apr;
67(13):e2200442.
PMID: 37099449
Scope: Modifications in intestinal microbiota and its metabolites, the short-chain fatty acids (SCFA) are main factors altering intestinal epithelial barrier integrity and eliciting the onset of a meta-inflammation observed in...
5.
DAntongiovanni V, Pellegrini C, Antonioli L, Ippolito C, Segnani C, Benvenuti L, et al.
Neuroscientist
. 2023 Apr;
30(4):493-510.
PMID: 37052336
Several studies have provided interesting evidence about the role of the bidirectional communication between the gut and brain in the onset and development of several pathologic conditions, including inflammatory bowel...
6.
Colucci R, Fornai M, Antonioli L, Segnani C, Ippolito C, Pellegrini C, et al.
J Pharm Pharmacol
. 2022 Dec;
75(2):264-275.
PMID: 36477570
Objective: Gut fibrosis occurs under chronic inflammation. This study examined the effects of different cyclooxygenase (COX) inhibitors on fibrosis in the inflamed colon. Methods: Colitis was induced by 2,4-dinitrobenzenesulfonic acid...
7.
Bellini G, Benvenuti L, Ippolito C, Frosini D, Segnani C, Rettura F, et al.
Eur J Neurol
. 2022 Oct;
30(11):3440-3450.
PMID: 36263629
Background And Purpose: Changes in gut microbiota composition, enteric inflammation, impairments of the intestinal epithelial barrier and neuroplastic changes in the enteric nervous system have been reported in Parkinson's disease...
8.
Pellegrini C, DAntongiovanni V, Ippolito C, Segnani C, Antonioli L, Fornai M, et al.
Eur J Histochem
. 2021 Nov;
65(s1).
PMID: 34802221
Gastrointestinal dysfunctions represent the most common non-motor symptoms in Parkinson's disease (PD). Of note, changes in gut microbiota, impairments of intestinal epithelial barrier (IEB), bowel inflammation and neuroplastic rearrangements of...
9.
Pellegrini C, Fornai M, Benvenuti L, Colucci R, Caputi V, Palazon-Riquelme P, et al.
Br J Pharmacol
. 2021 May;
178(19):3924-3942.
PMID: 34000757
Background And Purpose: Enteric neurogenic/inflammation contributes to bowel dysmotility in obesity. We examined the role of NLRP3 in colonic neuromuscular dysfunctions in mice with high-fat diet (HFD)-induced obesity. Experimental Approach:...
10.
Lucarini E, Parisio C, Branca J, Segnani C, Ippolito C, Pellegrini C, et al.
Cells
. 2020 Jul;
9(8).
PMID: 32722246
The management of visceral pain is a major clinical problem in patients affected by gastrointestinal disorders. The poor knowledge about pain chronicization mechanisms prompted us to study the functional and...