Cristin Aubin
Overview
Explore the profile of Cristin Aubin including associated specialties, affiliations and a list of published articles.
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13
Citations
2445
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Recent Articles
1.
Bennett D, Yu L, Yang J, Srivastava G, Aubin C, De Jager P
Transl Res
. 2014 Jun;
165(1):200-20.
PMID: 24905038
Alzheimer's disease (AD) is a large and growing public health problem. It is characterized by the accumulation of amyloid β peptides and abnormally phosphorylated tau proteins that are associated with...
2.
De Jager P, Shulman J, Chibnik L, Keenan B, Raj T, Wilson R, et al.
Neurobiol Aging
. 2011 Nov;
33(5):1017.e1-15.
PMID: 22054870
Age-related cognitive decline is likely promoted by accumulated brain injury due to chronic conditions of aging, including neurodegenerative and vascular disease. Because common neuronal mechanisms may mediate the adaptation to...
3.
Sawcer S, Hellenthal G, Pirinen M, Spencer C, Patsopoulos N, Moutsianas L, et al.
Nature
. 2011 Aug;
476(7359):214-9.
PMID: 21833088
Multiple sclerosis is a common disease of the central nervous system in which the interplay between inflammatory and neurodegenerative processes typically results in intermittent neurological disturbance followed by progressive accumulation...
4.
Chibnik L, Shulman J, Leurgans S, Schneider J, Wilson R, Tran D, et al.
Ann Neurol
. 2011 Mar;
69(3):560-9.
PMID: 21391232
Objective: Recently, genome-wide association studies have identified 3 new susceptibility loci for Alzheimer's disease (AD), CLU, CR1, and PICALM. We leveraged available neuropsychological and autopsy data from 2 cohort studies...
5.
Shulman J, Chipendo P, Chibnik L, Aubin C, Tran D, Keenan B, et al.
Am J Hum Genet
. 2011 Feb;
88(2):232-8.
PMID: 21295279
We have leveraged a Drosophila model relevant to Alzheimer disease (AD) for functional screening of findings from a genome-wide scan for loci associated with a quantitative measure of AD pathology...
6.
Shulman J, Chibnik L, Aubin C, Schneider J, Bennett D, De Jager P
PLoS One
. 2010 Jun;
5(6):e11244.
PMID: 20574532
Background: Recent genetic studies have identified a growing number of loci with suggestive evidence of association with susceptibility to Alzheimer's disease (AD). However, little is known of the role of...
7.
Zuvich R, McCauley J, Oksenberg J, Sawcer S, De Jager P, Aubin C, et al.
Hum Genet
. 2010 Jan;
127(5):525-35.
PMID: 20112030
Multiple sclerosis (MS) is characterized as an autoimmune demyelinating disease. Numerous family studies have confirmed a strong genetic component underlying its etiology. After several decades of frustrating research, the advent...
8.
De Jager P, Chibnik L, Cui J, Reischl J, Lehr S, Simon K, et al.
Lancet Neurol
. 2009 Nov;
8(12):1111-9.
PMID: 19879194
Background: Prediction of susceptibility to multiple sclerosis (MS) might have important clinical applications, either as part of a diagnostic algorithm or as a means to identify high-risk individuals for prospective...
9.
De Jager P, Jia X, Wang J, de Bakker P, Ottoboni L, Aggarwal N, et al.
Nat Genet
. 2009 Jun;
41(7):776-82.
PMID: 19525953
We report the results of a meta-analysis of genome-wide association scans for multiple sclerosis (MS) susceptibility that includes 2,624 subjects with MS and 7,220 control subjects. Replication in an independent...
10.
De Jager P, Baecher-Allan C, Maier L, Arthur A, Ottoboni L, Barcellos L, et al.
Proc Natl Acad Sci U S A
. 2009 Feb;
106(13):5264-9.
PMID: 19237575
Multiple sclerosis (MS) is an inflammatory disease of the central nervous system associated with demyelination and axonal loss. A whole genome association scan suggested that allelic variants in the CD58...