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Craig A McElroy

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Articles 38
Citations 436
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Recent Articles
11.
Tedeschi A, Larson M, Zouridakis A, Mo L, Bordbar A, Myers J, et al.
Brain . 2022 Jul; 145(7):2378-2393. PMID: 35905466
Stroke causes devastating sensory-motor deficits and long-term disability due to disruption of descending motor pathways. Restoration of these functions enables independent living and therefore represents a high priority for those...
12.
Lu Y, Vibhute S, Li L, Okumu A, Ratigan S, Nolan S, et al.
J Med Chem . 2021 Oct; 64(20):15214-15249. PMID: 34614347
Novel bacterial topoisomerase inhibitors (NBTIs) are among the most promising new antibiotics in preclinical/clinical development. We previously reported dioxane-linked NBTIs with potent antistaphylococcal activity and reduced hERG inhibition, a key...
13.
Abdelhameed A, Feng M, Joice A, Zywot E, Jin Y, La Rosa C, et al.
ACS Infect Dis . 2021 Feb; 7(7):1901-1922. PMID: 33538576
Due to the limitations of existing medications, there is a critical need for new drugs to treat visceral leishmaniasis. Since arylimidamides and antifungal azoles both show oral activity in murine...
14.
Venkataraman L, Fair S, McElroy C, Hester M, Fu H
Stem Cell Rev Rep . 2020 Nov; 18(2):696-717. PMID: 33180261
Many neurodegenerative diseases (NDs) such as Alzheimer's disease, Parkinson's disease, frontotemporal dementia, amyotrophic lateral sclerosis and Huntington's disease, are characterized by the progressive accumulation of abnormal proteinaceous assemblies in specific...
15.
Fair S, Julian D, Hartlaub A, Pusuluri S, Malik G, Summerfied T, et al.
Stem Cell Reports . 2020 Sep; 15(4):855-868. PMID: 32976764
Cerebral organoids (COs) are rapidly accelerating the rate of translational neuroscience based on their potential to model complex features of the developing human brain. Several studies have examined the electrophysiological...
16.
Corrigan T, Lotti Diaz L, Border S, Ratigan S, Kasper K, Sojka D, et al.
J Enzyme Inhib Med Chem . 2020 Jul; 35(1):1387-1402. PMID: 32633155
Aza-peptide aldehydes and ketones are a new class of reversible protease inhibitors that are specific for the proteasome and clan CD cysteine proteases. We designed and synthesised aza-Leu derivatives that...
17.
McGarry K, Lalisse R, Moyer R, Johnson K, Tallan A, Winters T, et al.
Toxicol Sci . 2020 May; 177(1):300. PMID: 32458003
No abstract available.
18.
Kackley M, Short J, Hyde P, LaFountain R, Buga A, Miller V, et al.
J Am Coll Nutr . 2020 Apr; 39(4):290-300. PMID: 32330107
Acute ingestion of ketone supplements alters metabolism and potentially exercise performance. No studies to date have evaluated the impact of co-ingestion of ketone salts with caffeine and amino acids on...
19.
McGarry K, Lalisse R, Moyer R, Johnson K, Tallan A, Winters T, et al.
Toxicol Sci . 2019 Dec; 174(1):133-146. PMID: 31879758
Chemical warfare nerve agents (CWNAs) present a global threat to both military and civilian populations. The acute toxicity of CWNAs stems from their ability to effectively inhibit acetylcholinesterase (AChE). This...
20.
Junaid Dar M, McElroy C, Khan M, Satoskar A, Khan G
Expert Opin Drug Deliv . 2019 Dec; 17(1):97-110. PMID: 31786952
: To test the hypothesis that miltefosine (MTF)-polyphenol co-loaded second-generation nano-transfersomes (SGNTs) can be an effective approach for the topical treatment of cutaneous leishmaniasis (CL).: The co-loaded SGNTs with various...