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Cory R Nicholas

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Articles 14
Citations 1039
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Recent Articles
1.
Bershteyn M, Broer S, Parekh M, Maury Y, Havlicek S, Kriks S, et al.
Cell Stem Cell . 2023 Oct; 30(10):1331-1350.e11. PMID: 37802038
Mesial temporal lobe epilepsy (MTLE) is the most common focal epilepsy. One-third of patients have drug-refractory seizures and are left with suboptimal therapeutic options such as brain tissue-destructive surgery. Here,...
2.
Raju C, Spatazza J, Stanco A, Larimer P, Sorrells S, Kelley K, et al.
Cereb Cortex . 2017 Apr; 28(6):1946-1958. PMID: 28449024
The neocortex of primates, including humans, contains more abundant and diverse inhibitory neurons compared with rodents, but the molecular foundations of these observations are unknown. Through integrative gene coexpression analysis,...
3.
Fandel T, Trivedi A, Nicholas C, Zhang H, Chen J, Martinez A, et al.
Cell Stem Cell . 2016 Sep; 19(4):544-557. PMID: 27666009
Neuropathic pain and bladder dysfunction represent significant quality-of-life issues for many spinal cord injury patients. Loss of GABAergic tone in the injured spinal cord may contribute to the emergence of...
4.
Pollen A, Nowakowski T, Chen J, Retallack H, Sandoval-Espinosa C, Nicholas C, et al.
Cell . 2015 Sep; 163(1):55-67. PMID: 26406371
Radial glia, the neural stem cells of the neocortex, are located in two niches: the ventricular zone and outer subventricular zone. Although outer subventricular zone radial glia may generate the...
5.
Southwell D, Nicholas C, Basbaum A, Stryker M, Kriegstein A, Rubenstein J, et al.
Science . 2014 Apr; 344(6180):1240622. PMID: 24723614
Many neurologic and psychiatric disorders are marked by imbalances between neural excitation and inhibition. In the cerebral cortex, inhibition is mediated largely by GABAergic (γ-aminobutyric acid-secreting) interneurons, a cell type...
6.
Chen Y, Vogt D, Wang Y, Visel A, Silberberg S, Nicholas C, et al.
PLoS One . 2013 May; 8(5):e61956. PMID: 23658702
The medial ganglionic eminence (MGE) is an embryonic forebrain structure that generates the majority of cortical interneurons. MGE transplantation into specific regions of the postnatal central nervous system modifies circuit...
7.
Nicholas C, Chen J, Tang Y, Southwell D, Chalmers N, Vogt D, et al.
Cell Stem Cell . 2013 May; 12(5):573-86. PMID: 23642366
Directed differentiation from human pluripotent stem cells (hPSCs) has seen significant progress in recent years. However, most differentiated populations exhibit immature properties of an early embryonic stage, raising concerns about...
8.
Nicholas C, Pera R
CSH Protoc . 2011 Mar; 2008:pdb.prot5045. PMID: 21356914
INTRODUCTIONThe potential for human embryonic stem cells (hESCs) to differentiate into all three embryonic germ layers, and the germline, can be used as a tool to understand the mechanisms of...
9.
Nicholas C, Kriegstein A
Nature . 2010 Feb; 463(7284):1031-2. PMID: 20182502
No abstract available.
10.
Nicholas C, Haston K, Pera R
BMC Dev Biol . 2010 Jan; 10:2. PMID: 20064216
Background: Female reproductive potential, or the ability to propagate life, is limited in mammals with the majority of oocytes lost before birth. In mice, surviving perinatal oocytes are enclosed in...