Cornelis B H W Lamers
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Explore the profile of Cornelis B H W Lamers including associated specialties, affiliations and a list of published articles.
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30
Citations
785
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Recent Articles
1.
Koelink P, Mieremet-Ooms M, Corver W, Wolanin K, Hommes D, Lamers C, et al.
Inflamm Bowel Dis
. 2009 Sep;
16(3):379-89.
PMID: 19774649
Introduction: Epidemiological data suggests that 5-aminosalicylic acid (5-ASA), a nonsteroidal antiinflammatory drug used in the treatment of inflammatory bowel diseases, prevents colorectal cancer development in these patients, although the mechanisms...
2.
Koelink P, Hawinkels L, Wiercinska E, Sier C, Ten Dijke P, Lamers C, et al.
Cancer Lett
. 2009 Jun;
287(1):82-90.
PMID: 19541409
The transforming growth factor-beta (TGF-beta) pathway is an important pathway in the initiation and progression of colorectal cancer. We aimed to determine the effects of 5-aminosalicylic acid (5-ASA) on TGF-beta...
3.
Hawinkels L, Verspaget H, van der Reijden J, van der Zon J, Verheijen J, Hommes D, et al.
Cancer Sci
. 2009 May;
100(4):663-70.
PMID: 19462508
Transforming growth factor-beta1 (TGF-beta1), a cytokine involved in various stages of cancer, is produced as a latent complex and requires processing to become active. We have determined total and active...
4.
Koelink P, Robanus-Maandag E, Devilee P, Hommes D, Lamers C, Verspaget H
Carcinogenesis
. 2009 May;
30(7):1217-24.
PMID: 19420017
Genetic predisposition, life-style habits and inflammatory bowel diseases (IBD)-related colitis are a main risk factor for colorectal cancer (CRC). 5-Aminosalicylic acid (5-ASA, mesalazine) is a mainstay therapy in IBD and...
5.
Hawinkels L, Zuidwijk K, Verspaget H, de Jonge-Muller E, van Duijn W, Ferreira V, et al.
Eur J Cancer
. 2008 Aug;
44(13):1904-13.
PMID: 18691882
Angiogenesis is crucial for the progression of colorectal carcinomas in which the bioavailability of Vascular Endothelial Growth Factor (VEGF) plays a major role. VEGF bioavailability is regulated by proteolytic release...
6.
Langers P, Press R, den Hartigh J, Cremers S, Baranski A, Lamers C, et al.
Ther Drug Monit
. 2008 Jul;
30(4):456-61.
PMID: 18641539
Trough (C0) monitoring is not optimal for therapeutic drug monitoring of tacrolimus. To better estimate systemic exposure of tacrolimus and achieve clinical benefit, an improved therapeutic drug monitoring strategy should...
7.
Meijer M, Mieremet-Ooms M, Sier C, van Hogezand R, Lamers C, Hommes D, et al.
Inflamm Bowel Dis
. 2008 Jul;
15(1):84-92.
PMID: 18634035
Background: Recurrence of disease after surgically induced remission constitutes a major and largely unpredictable problem in Crohn's disease (CD). Matrix metalloproteinases (MMP) and the tissue inhibitors of metalloproteinases (TIMP) are...
8.
ter Beek W, Muller E, van den Berg M, Meijer M, Biemond I, Lamers C
Inflamm Bowel Dis
. 2008 Jan;
14(5):612-9.
PMID: 18183601
Background: Besides regulation of upper gastrointestinal motility, motilin seems to play a role in the inflammatory response. Motilin receptor expression in human intestine has not been studied thoroughly. This study...
9.
Korstanje A, van Eeden S, Offerhaus J, Waltman F, den Hartog G, Roelandse F, et al.
J Clin Gastroenterol
. 2007 Dec;
42(1):18-22.
PMID: 18097284
Goals: To assess serologically diagnosed gastric body atrophy (GBA) by histology in a sample of the general population. Background: GBA is a precursor lesion in gastric cancer. Data on GBA...
10.
Eradication of Helicobacter pylori infection favourably affects altered gastric mucosal MMP-9 levels
Kubben F, Sier C, Schram M, Witte A, Veenendaal R, van Duijn W, et al.
Helicobacter
. 2007 Sep;
12(5):498-504.
PMID: 17760717
Background: Helicobacter pylori gastritis is recognized as an important pathogenetic factor in peptic ulcer disease and gastric carcinogenesis, and is accompanied by strongly enhanced gastric mucosal matrix metalloproteinase-9 (MMP-9) levels....