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Cormac Gm Gahan

Explore the profile of Cormac Gm Gahan including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 125
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Recent Articles
1.
Pinheiro J, Lyons T, Las Heras V, Recio M, Gahan C, OSullivan T
Future Med Chem . 2023 Mar; 15(4):317-332. PMID: 36927104
is a Gram-negative marine bacterium that is a model system in the study of quorum sensing (QS). uses multichannel QS, mediated by three signaling molecules. The aim of this study...
2.
Lyons T, Gahan C, OSullivan T
Future Med Chem . 2020 Oct; 12(21):1925-1943. PMID: 33094640
Since their initial isolation from the marine alga , bromofuranones have been investigated as potential inhibitors of quorum sensing (QS) in various bacterial strains. QS is an important mechanism by...
3.
Pereira-Fantini P, Bines J, Lapthorne S, Fouhy F, Scurr M, Cotter P, et al.
J Gastroenterol Hepatol . 2016 Apr; 31(12):1946-1955. PMID: 27037739
Background And Aim: Short bowel syndrome (SBS) is primarily characterized by malabsorption and malnutrition, resulting from loss of intestinal absorptive area following massive small bowel resection (SBR). Bile acids and...
4.
Casey P, Hill C, Gahan C
Bioeng Bugs . 2011 Jul; 2(4):189-93. PMID: 21715980
The 2011 German E. coli O104:H4 outbreak resulted in thousands of cases of enterohaemorrhagic illness, with approximately 25% of these progressing to develop haemolytic uraemic syndrome (HUS). This high rate...
5.
Fenton M, Casey P, Hill C, Gahan C, Ross R, McAuliffe O, et al.
Bioeng Bugs . 2011 Apr; 1(6):404-7. PMID: 21468207
The endolysin LysK derived from staphylococcal phage K has previously been shown to have two enzymatic domains, one of which is an N-acetylmuramoyl-L-alanine amidase and the other a cysteine/histidine-dependant amidohydrolase/peptidase...
6.
Bahey-El-Din M, Casey P, Griffin B, Gahan C
Bioeng Bugs . 2011 Feb; 1(1):66-74. PMID: 21327128
Listeria monocytogenes is a significant food-borne pathogen and the causative agent of listeriosis, a disease which manifests as meningitis in immunocompromised adults or infection of the fetus and miscarriage in...
7.
McLaughlin H, Hill C, Gahan C
Curr Opin Biotechnol . 2010 Nov; 22(2):194-9. PMID: 21093251
As iron is vital for all cells, host sequestration of iron provides a significant barrier to bacterial infection. The absolute requirement for iron has driven the evolution of refined systems...
8.
Bahey-El-Din M, Griffin B, Gahan C
Microb Cell Fact . 2008 Jul; 7:24. PMID: 18664263
Background: Listeria monocytogenes is a well-characterized food-borne pathogen that infects pregnant women and immunocompromised individuals. Listeriolysin O (LLO) is the major virulence factor of the pathogen and is often used...
9.
Monk I, Casey P, Cronin M, Gahan C, Hill C
BMC Microbiol . 2008 Jun; 8:96. PMID: 18554399
Background: The foodborne, gram-positive pathogen, Listeria monocytogenes, is capable of causing lethal infections in compromised individuals. In the post genomic era of L. monocytogenes research, techniques are required to identify...